Table 1 Baseline characteristics in patients
|  | All (N = 1334) | Males (N = 704) | Females (N = 630) | P value | |
|---|---|---|---|---|---|
Age, years, mean ± SD | 61.0 ± 10.1 | 59.3 ± 10.9 | 62.9 ± 8.8 | 0.000 | |
BMI, (kg/m2), IQR | 25.5 (23.5–27.8) | 25.7 (23.9–27.8) | 25.4 (23.4–27.6) | 0.062 | |
Hypertension, (%) | 847 (63.5) | 445 (63.2) | 402 (63.8) | 0.820 | |
Diabetes mellitus, (%) | 430 (32.2) | 213 (30.3) | 217 (34.4) | 0.102 | |
Hypercholesterolemia, (%) | 278(20.8) | 134 (19.0) | 144 (22.9) | 0.086 | |
Smoking history, (%) | 318 (23.8) | 304 (43.2) | 14 (2.2) | 0.000 | |
Family history of CAD, (%) | 15 (1.1) | 10 (1.4) | 5 (0.8) | 0.278 | |
Aspirin/Clopidogrel, (%) | 1143 (85.7) | 613 (87.1) | 530 (84.1) | 0.125 | |
Beta-blocker, (%) | 692 (51.9) | 350 (49.7) | 342 (54.3) | 0.095 | |
CCB, (%) | 298 (22.3) | 156 (22.2) | 142 (22.5) | 0.868 | |
ACEI, (%) | 131 (9.8) | 69 (9.8) | 62 (9.8) | 0.980 | |
Statin, (%) | 1203 (90.2) | 628 (89.2) | 575 (91.3) | 0.206 | |
Right Dominance | 1213 (90.9) | 630 (89.5) | 583 (92.5) | 0.053 | |
left Dominance | 121 (9.1) | 74 (10.5) | 47 (7.5) | 0.053 | |
Obstructive CAD, (%) | 580 (43.5) | 361 (51.3) | 219 (34.8) | 0.000 | |
Maximum Severe (≥ 70%) | 337 (25.3) | 195 (27.7) | 142(22.5) | 0.030 | |
Lesion Location | |||||
Left main to LAD | 283 (21.2) | 181 (25.7) | 102 (16.2) | 0.000 | |
LCX | 224 (16.8) | 135 (19.2) | 89 (14.1) | 0.014 | |
RCA | 173 (13.0) | 95 (13.5) | 78 (12.4) | 0.546 | |
FAI[LAD] (HU), IQR | -84 (-89–79) | -82 (-88–77) | -85 (-90–80) | 0.000 | |
FAI[LCX] (HU), IQR | -81 (-86–75) | -78 (-83–74) | -83 (-88–78) | 0.000 | |
FAI[RCA] (HU), IQR | -87 (-92–81) | -84 (-90–79) | -89 (-94–83) | 0.000 | |
FAI ≥ −70.1, (%) | |||||
FAI[LAD] ≥ −70.1, (%) | 83 (6.2) | 53 (7.5) | 30 (4.8) | 0.037 | |
FAI[LCX] ≥ −70.1, (%) | 163 (12.2) | 107(15.2) | 56 (8.9) | 0.000 | |
FAI[RCA] ≥ −70.1, (%) | 73 (5.5) | 42 (6.0) | 31 (4.9) | 0.402 | |
CT-FFR, IQR | 0.88 (0.74–0.93) | 0.84 (0.70–0.92) | 0.90 (0.79–0.93) | 0.000 | |
CT-FFR ≤ 0.80, (%) | 494 (37.0) | 321 (45.6) | 173 (27.5) | 0.000 | |
Cardiac catheterization, (%) | 290 (21.7) | 171 (24.3) | 119 (18.9) | 0.017 | |
MACE, (%) | 212 (15.9) | 120 (17.0) | 92 (14.6) | 0.223 | |
All-cause death, (%) | 20 (1.5) | 12 (1.7) | 8 (1.3) | 0.514 | |
Nonfatal MI, (%) | 129 (9.7) | 72 (10.2) | 57 (9.0) | 0.467 | |
Unplaned revascularzation, (%) | 33 (2.5) | 18 (2.6) | 15 (2.4) | 0.836 | |
Stroke, (%) | 12 (0.9) | 7 (1.0) | 5 (0.8) | 0.698 | |
Rehospitalisation for heart failure, (%) | 18 (1.3) | 11 (1.6) | 7 (1.1) | 0.476 | |