Table 5 Risk of major bleeding events of anticoagulant AF patients based on CHA₂DS₂-VASc score

Any OACs cohort

CHA₂DS₂-VASc of 0–1

- OACs

0.97 (0.36–2.11)

11.37 (0.95-135.37)

0.054

- No OACs

0.15 (0.01–0.82)

Reference

CHA₂DS₂-VASc of 2 or more

- OACs

2.68 (2.23–3.18)

2.29 (1.26–4.14)

0.006*

- No OACs

1.56 (0.93–2.47)

Reference

Warfarin cohort

CHA₂DS₂-VASc of 0–1

- Warfarin

1.16 (0.42–2.51)

13.69 (1.18–159.40)

0.037*

- No OACs

0.15 (0.01–0.82)

Reference

CHA₂DS₂-VASc of 2 or more

- Warfarin

2.77 (2.30–3.31)

2.38 (1.32–4.32)

0.004*

- No OACs

1.56 (0.93–2.47)

Reference

DOACs cohort

CHA₂DS₂-VASc of 0–1

- DOACs

-

-

-

- No OACs

0.15 (0.01–0.82)

Reference

CHA₂DS₂-VASc of 2 or more

- DOACs

1.60 (0.60–3.53)

3.62 (0.88–14.80)

0.074

- No OACs

1.56 (0.93–2.47)

Reference