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Table 3 Risk of thromboembolic events of atrial fibrillation patients based on CHA2DS2-VASc score and oral anticoagulants (OACs)

From: Net clinical benefit of oral anticoagulants in Asian patients with atrial fibrillation based on a CHA2DS2-VASc score

Antithrombotic strategy

Thromboembolic events

Annual incidence rate

Adjusted HR (95%CI)

P value

Any OACs cohort

CHA2DS2-VASc of 0–1

- OACs

0.16 (0.01–0.90)

0.13 (0.01–1.49)

0.100

- No OACs

1.03 (0.41–2.12)

Reference

CHA2DS2-VASc of 2 or more

- OACs

1.52 (1.19–1.91)

0.74 (0.41–1.34)

0.740

- No OACs

2.34 (1.55–3.42)

Reference

Warfarin cohort

CHA2DS2-VASc of 0–1

- Warfarin

0.19 (0.01–1.07)

0.13 (0.01–1.57)

0.108

- No OACs

1.03 (0.41–2.12)

Reference

CHA2DS2-VASc of 2 or more

- Warfarin

1.58 (1.23-2.00)

0.77 (0.43–1.40)

0.391

- No OACs

2.34 (1.55–3.42)

Reference

DOACs cohort

CHA2DS2-VASc of 0–1

- DOACs

-

-

-

- No OACs

1.03 (0.41–2.12)

Reference

CHA2DS2-VASc of 2 or more

- DOACs

0.8 (0.17–2.37)

0.56 (0.13–2.48)

0.444

- No OACs

2.34 (1.55–3.42)

Reference

  1. AF = atrial fibrillation, HR = hazard ratio, 95%CI = 95% confidence interval, OACs = oral anticoagulants, DOACs = direct oral anticoagulants
  2. Variables for adjusted: Symptoms and pattern of AF, CIEDs, dyslipidemia, CKD, dementia, a history of bleeding, alcohol use, LVEF < 50%, antiplatelet drugs