Net clinical benefit of oral anticoagulants in Asian patients with atrial fibrillation based on a CHA2DS2-VASc score

Table 2 Annual thromboembolic events in atrial fibrillation patients with or without oral anticoagulants (OACs) stratified by CHA₂DS₂-VASc score (CI = confidence interval)

CHA₂DS₂-VASc score	Number of patients	Number of events	100 person-years	Rate per 100 person-years	95% CI
All patients
0	196	3	4.0	0.74	0.15–2.19
1	422	5	8.9	0.56	0.18–1.31
2	694	14	14.5	0.96	0.53–1.62
3	782	17	16.7	1.02	0.59–1.63
4	618	26	13.0	2.01	1.31–2.93
5	419	17	9.1	1.86	1.09–2.99
≥ 6	271	25	5.6	4.43	2.89–6.59
Total	3402	107	71.9	1.49	1.22–1.80
OACs
0	61	1	1.3	0.77	0.02–4.29
1	236	0	4.9	0.00	-
2	539	12	11.0	1.09	0.56–1.91
3	641	12	13.6	0.88	0.46–1.54
4	515	18	10.6	1.69	1.00-2.68
5	352	11	7.6	1.44	0.72–2.59
≥ 6	222	19	4.6	4.11	2.49–6.459
Total	2566	73	53.6	1.36	1.07–1.71
No OACs
0	135	2	2.7	0.73	0.09–2.68
1	186	5	4.0	1.24	0.41–2.92
2	155	2	3.5	0.56	0.07–2.06
3	141	5	3.1	1.61	0.52–3.76
4	103	8	2.3	3.44	1.50–6.85
5	67	6	1.5	3.97	1.47–8.71
≥ 6	49	6	1.0	5.83	2.20-13.06
Total	836	34	18.3	1.86	1.29–2.60

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