Skip to main content

Table 3 Nonlinearity Addressed through Two-piecewise Linear Model

From: Association of systemic immune inflammatory index with all-cause and cause-specific mortality among individuals with type 2 diabetes

 

All-cause mortality

P

CVD mortality

P

Cancer mortality

P

Threshold value

6.03

 

6.22

 

6.07

 

< Threshold value

0.64(0.48,0.86)

0.003

1.07(0.68,1.69)

0.76

0.30(0.17,0.53)

< 0.001

> Threshold value

1.92(1.65,2.25)

< 0.001

2.55(1.69,3.84)

< 0.001

2.51(1.75,3.61)

< 0.001

  1. Notes: hazard ratios were calculated based on multivariable Cox proportional hazards regression model adjusted for age (continuous), sex (male or female) and ethnicity (non-Hispanic white, non-Hispanic black, Mexican American, or other), BMI (< 25, 25–30, ≥ 30 kg/m2), education level (less than high school, high school or equivalent, or college or above), family income-poverty ratio (0–1.0, 1.0–3.0, or > 3.0), smoking status (never smoker, current smoker, or former smoker), drinking status (non-drinker, low-to-moderate drinker, heavy drinker, or former drinker), duration of diabetes (≤ 3, 3–10, or > 10 years), diabetic medication use (none, only oral medication, insulin, or others), HbA1c (< 7%, or ≥ 7%), hypertension, hyperlipidemia, ASCVD, CKD (yes, or no). Abbreviations: CVD, cardiovascular disease