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Table 2 Multivariable Cox Regression Analyses for Mortality among Participants with Diabetes

From: Association of systemic immune inflammatory index with all-cause and cause-specific mortality among individuals with type 2 diabetes

 

lnSII

Per SD increment in lnSII

 

≤ 5.84

5.84–6.19

6.19–6.55

> 6.55

Ptrend

All-cause mortality

      

 Death, No./total No.

510/2165

547/2168

614/2170

792/2165

  

 Model 1

Reference

0.99(0.85,1.16)

0.97(0.81,1.15)

1.44(1.25,1.65)

< 0.001

1.21(1.14,1.28)

 Model 2

Reference

0.94(0.79,1.13)

0.97(0.79,1.18)

1.42(1.19,1.68)

< 0.001

1.21(1.12,1.30)

 Model 3

Reference

0.95(0.79,1.16)

0.92(0.75,1.12)

1.33(1.10,1.61)

0.002

1.17(1.07,1.26)

CVD mortality

      

 Death, No.

178

191

220

264

  

 Model 1

Reference

1.10(0.89,1.37)

1.03(0.77,1.37)

1.65(1.25,2.18)

< 0.001

1.33(1.19,1.50)

 Model 2

Reference

0.96(0.75,1.24)

1.05(0.77,1.43)

1.63(1.19,2.25)

0.002

1.38(1.20,1.58)

 Model 3

Reference

1.03(0.79,1.34)

1.07(0.77,1.50)

1.59(1.11,2.27)

0.01

1.34(1.15,1.57)

Cancer mortality

      

 Death, No.

100

97

93

134

  

 Model 1

Reference

0.77(0.52,1.15)

0.67(0.45,0.99)

1.09(0.77,1.54)

0.69

1.07(0.90,1.28)

 Model 2

Reference

0.65(0.41,1.01)

0.60(0.39,0.93)

1.02(0.68,1.53)

0.81

1.04(0.84,1.28)

 Model 3

Reference

0.61(0.38,0.96)

0.59(0.38,0.91)

0.95(0.62,1.44)

0.96

0.99(0.80,1.23)

  1. Notes: Model 1: adjusted for age (continuous), sex (male or female) and ethnicity (non-Hispanic white, non-Hispanic black, Mexican American, or other); Model 2: further adjusted for BMI (< 25, 25–30, ≥ 30 kg/m2), education level (less than high school, high school or equivalent, or college or above), family income-poverty ratio (0–1.0, 1.0–3.0, or > 3.0), smoking status (never smoker, current smoker, or former smoker), drinking status (non-drinker, low-to-moderate drinker, heavy drinker, or former drinker); Model 3: further adjusted for duration of diabetes (≤ 3, 3–10, or > 10 years), diabetic medication use (none, only oral medication, insulin, or others), HbA1c (< 7%, or ≥ 7%), hypertension, hyperlipidemia, ASCVD, CKD (yes, or no). Abbreviationss: CVD, cardiovascular disease; SII, systemic immune inflammation
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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