Table 3 Baseline correlations between sphingolipids and ceramides and key measures of cardiac structure and function

Sphingomyelin species

 Hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH))

-0.348^a

0.117

0.042

0.226

0.463^b

0.105

-0.207

 Sphingomyelin (d18:2/16:0, d18:1/16:1)

-0.320^a

0.123

-0.032

0.279

0.325^a

0.033

0.330

 Sphingomyelin (d18:2/24:1, d18:1/24:2)

-0.384^b

0.211

-0.185

0.336^a

0.408^b

0.263

-0.198

 Sphingomyelin (d18:1/22:2, d18:2/22:1, d16:1/24:2)

-0.177

0.201

0.032

0.368^b

0.423^b

0.037

0.084

 Sphingomyelin (d18:1/20:2, d18:2/20:1, d16:1/22:2)

-0.178

0.090

-0.048

0.249

0.361^a

-0.047

0.063

 Sphingomyelin (d18:2/18:1)

-0.188

0.057

-0.088

0.233

0.236

0.040

0.001

 Sphingomyelin (d18:2/23:1)

-0.138

0.207

-0.032

0.384^b

0.378^b

0.122

0.089

 Sphingomyelin (d18:2/24:2)

-0.264

0.216

-0.003

0.374^b

0.419^b

-0.037

0.020

Ceramide species

 Glycosyl ceramide (d18:2/24:1, d18:1/24:2)

-0.388^b

0.139

-0.137

0.344^b

0.340^a

0.212

-0.165

 Glycosyl-N-nervonoyl-sphingosine (d18:1/24:1)⁺

-0.395^b

0.063

-0.167

0.260

0.124

0.186

-0.058

 Lactosyl-N-nervonoyl-sphingosine (d18:1/24:1)

-0.473^b

0.079

-0.244

0.129

0.102

0.268

-0.266

 Lactosyl-N-palmitoyl-sphingosine (d18:1/16:0)

-0.458^b

-0.074

-0.226

-0.002

0.064

0.312^a

-0.363^a