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Table 1 Baseline characteristics of study population

From: Cardiovascular protective effect of sodium-glucose cotransporter 2 inhibitors on patients with acute coronary syndrome and type 2 diabetes mellitus: a retrospective study

 

SGLT-2i group

(n = 128)

Non-SGLT-2i group

(n = 104)

P value

Age, years

64 (56,70)

67 (57,71)

0.325

Male (%)

96 (75.0%)

79 (76.7%)

0.765

BMI, kg/m2

24.92 \(\pm 3.46\)

24.51 \(\pm 3.40\)

0.384

ACS (%)

  

0.174

 Unstable angina

44 (34.4%)

27 (26.0%)

 

 NSTEMI

33 (25.8%)

23 (22.1%)

 

 STEMI

51 (39.8%)

54 (51.9%)

 

Smoking (%)

70 (54.7%)

61 (58.7%)

0.545

Old stroke (%)

9 (7.0%)

6 (5.8%)

0.697

Hypertension (%)

89 (69.5%)

55 (52.9%)

0.009

CAD (%)

17 (13.3%)

19 (18.3%)

0.297

Congestive heart failure (%)

4 (3.1%)

0 (0.00%)

0.130

Duration of T2DM, years

1.0 (0,10)

3.5 (0,10)

0.255

High Risk of in-hospital death (%)

39 (30.5%)

39 (37.5%)

0.260

Gensini score

48.0 (24.0,80.0)

47.5 (22.8,82.0)

0.824

Coronary stenting (%)

100 (78.1%)

84 (80.8%)

0.621

Drugs

 Antiplatelet therapy (%)

128 (100%)

104 (100%)

 

 β-Blocker (%)

97 (75.8%)

80 (76.9%)

0.839

 Lipid-lowering therapy (%)

128 (100%)

104 (100%)

 

 ACEi/ARB/ARNi (%)

98 (76.6%)

67 (67.3%)

0.117

 CCBs (%)

21 (16.4%)

10 (9.6%)

0.131

 Diuretics (%)

25 (19.5%)

24 (23.1%)

0.511

 Insulin (%)

31 (24.2%)

27 (26.0%)

0.760

 Sulfonylurea (%)

15 (11.7%)

15 (14.4%)

0.542

 GLP-1 receptor agonist (%)

15 (11.7%)

9 (8.7%)

0.446

 DPP-IV Inhibitors (%)

3 (2.3%)

3 (2.9%)

0.796

 Metformin (%)

71 (55.5%)

60 (57.7%)

0.734

 Empagliflozin (%)

81 (63.3%)

0 (0%)

 

 Dapagliflozin (%)

47 (36.7%)

0 (0%)

 

Biochemical indicators

 HbA1c

7.60 (6.30,8.90)

7.40 (6.63,8.38)

0.635

 Scr, mmol/L

74 (62,89)

71 (59,84)

0.169

 UA, μmol/L

335 (272,409)

331 (277,390)

0.593

 TC, mmol/L

4.36 (3.66,5.04)

4.01 (3.40,4.94)

0.195

 HDL, mmol/L

0.96 (0.86,1.12)

0.95 (0.81,1.13)

0.346

 LDL, mmol/L

2.54 (1.99,3.19)

2.39 (1.76,3.14)

0.219

 LP(α), mmol/L

102 (57,290)

133 (46,391)

0.835

 hs-CRP, mg/dL

3.52 (1.68,10.94)

4.53 (1.44,12.45)

0.846

Echocardiographic

 LVEF (%)

59 (48,63)

58 (49,63)

0.516

 LAD (mm)

33 (31,36)

32 (30,35)

0.022

 LVIDd (mm)

48 (45,51)

48 (44,48)

0.969

 IVSd (mm)

10 (10,11)

10 (10.11)

0.537

 LVPWd (mm)

10 (10,11)

10 (10,11)

0.389

  1. CAD Coronary artery disease, CCB Calcium Channel Blocker, ACEi angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, ARNi Angiotensin receptor-neprilysin inhibitor, GLP-1 Glucagon Like Peptide 1, DPP-IV Dipeptidyl Peptidase IV, LVEF left ventricular ejection fraction, LAD left atrial diameter, LVIDd left ventricular end-diastolic diameter, IVSd interventricular septal thickness, LVPWd left ventricular posterior wall thickness