Skip to main content

Table 3 Subgroup analysis of the relationship between cystatin C and coronary atherosclerotic disorder

From: Association of serum cystatin C level with coronary atherosclerotic plaque burden: a comprehensive analysis of observational studies and genetic study

Characteristic

Group 1

(Ref)

 

Group 2

Group 3

 

OR(95%CI)

P value

OR(95%CI)

P value

Age (years old)

      

< 55

Ref

SSS (sev)

2.99 (0.97–9.18)

0.056

2.52 (0.60-10.56)

0.205

55–65

Ref

SSS (sev)

2.35 (1.26–4.39)

0.007

4.35 (2.18–8.71)

< 0.001

≥ 65

Ref

SSS (sev)

1.62 (0.76–3.45)

0.209

2.48 (1.81–5.20)

0.016

Gender

  

Male

Ref

SSS (sev)

2.11 (1.09–4.09)

0.027

2.06 (1.03–4.09)

0.040

Female

Ref

SSS (sev)

1.54 (0.84–2.80)

0.162

3.45 (1.86–6.37)

< 0.001

Diabetes

      

Yes

Ref

SSS (sev)

3.61 (1.48–8.81)

0.005

4.88 (1.94–12.25)

< 0.001

NO

Ref

SSS (sev)

1.44 (0.87–2.40)

0.157

2.14 (1.24–3.69)

0.007

Hypertension

      

Yes

Ref

SSS (sev)

1.76 (1.01–3.07)

0.048

2.85 (1.62-5.00)

< 0.001

NO

Ref

SSS (sev)

1.83 (0.90–3.74)

0.097

1.78 (0.81–3.93)

0.155

BMI, kg/m2

      

< 24

Ref

SSS (sev)

1.66 (0.39–6.99)

0.490

1.82 (0.38–8.69)

0.456

≥ 24

Ref

SSS (sev)

1.88 (1.19–2.97)

0.007

2.57 (1.60–4.12)

< 0.001

Renal disorder

  

Yes

Ref

SSS (sev)

2.06 (0.49–8.61)

0.320

2.78 (0.67–11.57)

0.159

NO

Ref

SSS (sev)

1.89 (1.19-3.00)

0.007

2.60 (1.59–4.27)

< 0.001

hyperuricemia

      

Yes

Ref

SSS (sev)

3.41 (0.71–16.27)

0.124

3.71 (0.80-17.19)

0.094

NO

Ref

SSS (sev)

1.78 (1.12–2.81)

0.014

2.55 (1.59–4.11)

< 0.001

  1. SIS: segment-involvement score; SSS: segment stenosis score