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Table 1 Baseline Characteristics of Participants

From: Association of serum cystatin C level with coronary atherosclerotic plaque burden: a comprehensive analysis of observational studies and genetic study

variable

Q1 (n = 979)

(0.52–0.85) mg/dL

Q2 (n = 1016)

(0.86–0.99) mg/dL

Q3 (n = 1048)

(1.00-7.35) mg/dL

P value

Age (years old)

58.2 ± 5.5

60.9 ± 6.4

64.3 ± 6.6

< 0.001

Man, n (%)

291(29.7)

469(46.2)

653(62.3)

< 0.001

BMI (kg/m2)

23.5 ± 3.0

23.7 ± 3.0

24.1 ± 3.1

< 0.001

SBP (mmHg)

127.5 ± 16.1

128.9 ± 16.3

131.2 ± 16.4

< 0.001

DBP (mmHg)

74.9 ± 8.9

75.1 ± 9.2

75.5 ± 9.0

0.3469

Hypertension (%)

325(33.2)

422(41.5)

557(53.1)

< 0.001

Diabetes (%)

186(19.0)

202(19.9)

270(25.8)

0.0003

dyslipidemia

378(38.6)

412(40.6)

479(45.7)

0.0035

Stroke

14(1.4)

23(2.3)

49(4.7)

< 0.001

renal_disorder

107(10.9)

121(11.9)

149(14.2)

0.0684

Smoking (%)

102(10.4)

212(20.9)

311(29.7)

< 0.001

Drinking (%)

171(17.5)

203(20.0)

194(18.5)

0.3500

waistline

84.8 ± 8.7

86.5 ± 8.6

88.7 ± 9.0

< 0.001

hipline

94.4 ± 6.3

95.0 ± 6.1

95.8 ± 6.4

< 0.001

Creatinine (umol/L)

57.9 ± 10.1

65.0 ± 11.2

76.4 ± 20.5

< 0.001

UA (umol/L)

303.0 ± 71.4

336.4 ± 75.0

378.0 ± 91.4

< 0.001

BUN (mmol/L)

5.5 ± 1.4

5.8 ± 1.4

6.2 ± 1.5

< 0.001

Cholesterol (mmol/L)

5.4 ± 1.0

5.3 ± 1.0

5.1 ± 1.0

< 0.001

LDL-C (mmol/L)

2.8 ± 0.8

2.8 ± 0.8

2.7 ± 0.8

< 0.001

HDL-C (mmol/L)

1.5 ± 0.3

1.4 ± 0.3

1.3 ± 0.3

< 0.001

LP(a) (mg/L)

60.0(32.0-146.0)

63.0(31.0-145.5)

64.0(33.0-159.0)

0.4178

Triglyceride (mmol/L)

1.7 ± 1.3

1.8 ± 1.2

1.9 ± 1.2

0.0002

Cys (mg/L)

0.8 ± 0.1

0.9 ± 0.0

1.2 ± 0.2

< 0.001

HbA1c

5.9 ± 0.9

5.9 ± 0.9

6.0 ± 1.0

0.0001

glu (mmol/L)

6.0 ± 1.6

5.9 ± 1.4

6.0 ± 1.7

0.6705

abil

1.1 ± 0.1

1.1 ± 0.1

1.1 ± 0.1

0.9851

abir

1.1 ± 0.1

1.1 ± 0.1

1.1 ± 0.4

0.9111

SIS (1–3)

299(30.5)

405(39.9)

503(48.0)

< 0.001

SIS (≥ 4)

15(1.5)

55(5.4)

88(8.4)

< 0.001

SSS (1–3)

238(24.3)

307(30.2)

355(33.9)

< 0.001

SSS (≥ 4)

33(3.4)

85(8.4)

168(16.0)

< 0.001

  1. BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; UA: uric acid; BUN: blood urea nitrogen; LDL: low density lipoprotein-Cholesterol; HDL: high density lipoprotein-Cholesterol; LP(a): lipoprotein(a); Cys: homocysteine; HbA1c: glycosylated hemoglobin; abil: ankle brachial index of left leg; abir: ankle brachial index of right leg; SIS: segment-involvement score; SSS: segment stenosis score
  2. Quartiles of cystatin C, mg/dL