Fig. 4

Allicin suppresses NLRP3 inflammasome activation by LPS in cardiomyocytes. H9c2 cells were pretreated with 50 µM Allicin, followed by incubation with LPS (10 µg/mL) for 24 h. (A) Representative western blot bands investigating NLRP3 pathway proteins. Quantitative results of western blot analysis on expressions of NLRP3 (B), pro-caspase-1 (C), cleaved caspase-1 (p10) protein (D), pro-IL-1β (E), and pro-IL-1β (F). ***P < 0.001 vs. control group; ###P < 0.001 vs. LPS group