Table 2 Clinical and genetic data of patients with PTTR ≥ 60% and PTTR < 60%

Age, y

47.94 ± 10.38

45.68 ± 10.20

0.006

 Age ≥ 50y

106 (36.81%)

92 (26.98%)

0.01

 Age < 50y

182 (63.19%)

249 (73.02%)

High, cm

161.17 ± 7.73

159.77 ± 7.75

0.025

Weight, kg

58.54 ± 10.19

56.60 ± 9.60

0.015

BMI

22.46 ± 3.17

22.12 ± 3.07

0.16

 BMI ≥ 24

53 (47.74%)

58 (52.25%)

0.67

 BMI < 24

235 (45.37%)

283 (54.63%)

Sexual, F/M

160 (55.56%)/128 (44.44%)

225 (65.98%)/116 (34.02%)

0.009

Smoking habit

35 (12.15%)

32 (9.23%)

0.30

Drinking history

21 (7.29%)

15 (4.40%)

0.12

MHVR

247 (44.26%)

311 (55.74%)

0.042

BHVR

41 (57.74%)

30 (42.26%)

AVR

166 (57.64%)

140 (41.06%)

9.08E-8

MVR

230 (79.86%)

291 (85.34%)

0.072

TVR

19 (6.60%)

14 (4.11%)

0.005

Hypertension

32 (11.11%)

26 (7.62%)

0.16

CHD

13 (4.51%)

6 (1.76%)

0.06

T2D

6 (2.08%)

7 (2.05%)

1.00

AF

133 (46.18%)

135 (39.59%)

0.11

Stroke history

18 (6.25%)

10 (2.93%)

0.052

MAZE

47 (16.32%)

52 (15.25%)

0.74

AF after surgery

86 (29.86%)

83 (24.34%)

0.13

Infectious endocarditis

11 (3.82%)

19 (5.57%)

0.35

Digestive tract disease

9 (3.13%)

5 (1.47%)

0.18

Gallbladder disorders

6 (2.08%)

15 (4.40%)

0.12

Hepatitis

7 (2.43%)

10 (2.93%)

0.81

Hyperthyroidism

8 (2.78%)

8 (2.35%)

0.80

Pausimenia

38 (13.19%)

55 (16.13%)

0.31

INR measurements, media (25th-75th IQR)

7 (7–11)

9 (8–11)

0.25

VKORC1

0.30

 AA

242 (84.03%)

275 (80.56%)

 AG + GG

46 (15.97%)

66 (19.35%)

CYP2C9

0.065

 *1*1

256 (88.89%)

318 (93.26%)

 *1*3

32 (11.11%)

23 (6.74%)