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Table 2 Associations between NPAR, NLR, PLR, and all-cause mortality in patients with HF

From: Association between neutrophil percentage-to-albumin ratio (NPAR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and long-term mortality in community-dwelling adults with heart failure: evidence from US NHANES 2005–2016

 

Univariate

 

Multivariable

 
 

Crude HR (95%CI)

P value

 

Adjusted HR (95%CI)

P value

 

In continuous

      

NPAR

1.12 (1.09, 1.15)

< 0.001

 

1.08 (1.05, 1.12)

< 0.001

 

NLR

1.09 (1.07, 1.12)

< 0.001

 

1.05 (1.02, 1.08)

0.004

 

PLR

1 (1.00, 1.00)

< 0.001

 

1 (1.00, 1.00)

0.3

 

In category

      

NPAR

      

Q1

Reference

  

Reference

  

Q2

1.52 (1.16, 1.97)

0.002

 

1.11 (0.81, 1.52)

0.5

 

Q3

1.62 (1.24, 2.10)

< 0.001

 

1.09 (0.80, 1.48)

0.6

 

Q4

2.83 (2.21, 3.64)

< 0.001

 

1.81 (1.35, 2.43)

< 0.001

 

NLR

      

Q1

Reference

  

Reference

  

Q2

1.51 (1.15, 1.98)

0.003

 

1.11 (0.81, 1.54)

0.5

 

Q3

2.14 (1.64, 2.78)

< 0.001

 

1.26 (0.93, 1.72)

0.14

 

Q4

2.91 (2.26, 3.76)

< 0.001

 

1.59 (1.18, 2.15)

0.002

 

PLR

      

Q1

Reference

  

Reference

  

Q2

1.08 (0.84, 1.39)

0.556

 

1.05 (0.79, 1.40)

0.7

 

Q3

1.25 (0.97, 1.60)

0.081

 

1.21 (0.91, 1.61)

0.2

 

Q4

1.45 (1.14, 1.83)

0.002

 

1.09 (0.83, 1.44)

0.5

 
  1. Multivariable analyses were adjusted for age (in years), gender, race, BMI (category), DM, CKD, COPD, history of MI, trouble sleeping, and diuretics usage. Bold P values indicate significance
  2. Abbreviations: NPAR, neutrophil-percentage-to-albumin ratio; PLR, platelet-to-lymphocyte ratio; NLR, neutrophil-to-lymphocyte ratio; Q, quartile; HR, hazard ratio; CI, confidence interval