Table 2 Statistical analysis of ADHF outcomes according to the ejection fraction at various time points

Total

4832

2222

5798

Outcomes

 6 months

  Primary outcomes

1314

(27.2)

533

(24.0)

1202

(20.7)

< 0.001

  All-cause mortality

727

(15.1)

290

(13.1)

834

(14.4)

0.086

  CV death

370

(7.7)

126

(5.7)

327

(5.6)

< 0.001

  HF rehospitalization

1054

(21.8)

436

(19.6)

962

(16.6)

< 0.001

  AMI

169

(3.5)

87

(3.9)

162

(2.8)

0.019

  Ischemic stroke

109

(2.3)

65

(2.9)

207

(3.6)

< 0.001

 1 year

  Primary outcomes

1679

(34.8)

710

(32.0)

1632

(28.2)

< 0.001

  All-cause mortality

1048

(21.7)

456

(20.5)

1274

(22.0)

0.364

  CV death

530

(11.0)

198

(8.9)

501

(8.6)

< 0.001

  HF rehospitalization

1348

(27.9)

572

(25.7)

1297

(22.4)

< 0.001

  AMI

230

(4.8)

126

(5.7)

233

(4.0)

0.009

  Ischemic stroke

151

(3.1)

107

(4.8)

283

(4.9)

< 0.001

 5 years

  Primary outcomes

2560

(53.0)

1120

(50.4)

2683

(46.3)

< 0.001

  All-cause mortality

2215

(45.8)

1074

(48.3)

2938

(50.7)

< 0.001

  CV death

1052

(21.8)

446

(20.1)

1090

(18.8)

< 0.001

  HF rehospitalization

2024

(41.9)

879

(39.6)

2067

(35.7)

< 0.001

  AMI

410

(8.5)

254

(11.4)

441

(7.6)

< 0.001

  Ischemic stroke

318

(6.6)

219

(9.9)

606

(10.5)

< 0.001

 Whole period

  Primary outcomes

2813

(58.2)

1253

(56.4)

2966

(51.2)

< 0.001

  All-cause mortality

2743

(56.8)

1361

(61.3)

3700

(63.8)

< 0.001

  CV death

1292

(26.7)

580

(26.1)

1386

(23.9)

< 0.001

  HF rehospitalization

2203

(45.6)

972

(43.7)

2241

(38.7)

< 0.001

  AMI

476

(9.9)

301

(13.6)

541

(9.3)

< 0.001

  Ischemic stroke

378

(7.8)

249

(11.2)

693

(12.0)

< 0.001

Follow years, mean (SD)

3.8

(3.6)

4.1

(3.6)

3.8

(3.6)

0.002