Factors associated with bleeding events from enoxaparin used for patients with acute coronary syndrome

Table 4 Risk factors for any bleeding (univariable analysis)

Characteristics	Odds ratio (95% CI)	p-value
Age ≥ 65 years	2.08 (1.24–3.48)	0.005*
SBP > 160 mmHg	1.37 (0.83–2.27)	0.223
Creatinine clearance, mL/min	1.00 (0.99–1.01)	0.453
Cerebrovascular disease	1.64 (0.94–2.85)	0.078*
Hypertension	1.78 (1.08–2.95)	0.023*
History of bleeding	4.21 (1.43–12.41)	0.014*
History of NSAIDs used	3.28 (1.26–8.56)	0.019*
History of oral anticoagulant used	5.09 (1.91–13.55)	0.002*
Anemia (Hemoglobin: male < 13 g/dL, female < 12 g/dL)	1.15 (0.74–1.79)	0.529
Conservative strategy	1.77 (1.03–3.06)	0.038*
Coronary artery angiography (CAG)	0.62 (0.38–1.02)	0.057*
Femoral access^a	1.91 (0.57–6.42)	0.286
Percutaneous coronary intervention (PCI)	1.01 (0.65–1.56)	0.977
Clopidogrel	0.55 (0.29–1.05)	0.066*
Ticagrelor	1.61 (0.74–3.49)	0.228
No. of enoxaparin doses	0.98 (0.95–1.02)	0.282

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