Variable | Normal | Lean | Overweight and 0bese | P-value |
---|---|---|---|---|
(n = 81) | (n = 17) | (n = 48) | ||
Age, years | 42.83 ± 13.07 | 27.94 ± 9.78† | 48.25 ± 9.42† | <0.001 |
Male, n(%) | 24(29.63) | 8(47.06) | 23(47.92)† | 0.082 |
Height, cm | 159.44 ± 6.21 | 163.59 ± 9.17† | 162.63 ± 8.96† | 0.025 |
Weight, kg | 53.94 ± 4.78 | 45.06 ± 5.17† | 70.44 ± 10.39† | <0.001 |
BSA, m2 | 1.51 ± 0.09 | 1.42 ± 0.12† | 1.74 ± 0.18† | <0.001 |
Diabetes, n(%) | 0(0) | 0(0) | 3(6.25)† | 0.044 |
Hypertension, n(%) | 9(11.11) | 1(5.88) | 8(16.67) | 0.455 |
Smoking, n(%) | 16(19.75) | 3(17.65) | 9(18.75) | 0.976 |
Alcohol consumption, n(%) | 11(13.58) | 2(11.76) | 14(29.17)† | 0.066 |
NYHA | ||||
I, n(%) | 2(2.47) | 0(0) | 0(0) | 0.449 |
II, n(%) | 56(69.13) | 13(76.47) | 26(54.17)† | 0.132 |
III, n(%) | 23(28.39) | 4(23.53) | 22(45.83)† | 0.084 |
LVFS, % | 36.64 ± 5.12 | 34.82 ± 2.04 | 36.92 ± 4.45 | 0.267 |
LVEF, % | 66.16 ± 7.31 | 64.94 ± 2.11 | 67.04 ± 4.99 | 0.465 |
LAD, mm | 34.51 ± 7.08 | 32.29 ± 4.71 | 37.01 ± 6.72† | 0.022 |
LVDs, mm | 42.68 ± 7.06 | 40.53 ± 6.51 | 43.92 ± 6.68 | 0.211 |
RAD, mm | 37.79 ± 7.36 | 38.01 ± 9.51 | 37.27 ± 7.47 | 0.914 |
RVDs, mm | 27.37 ± 8.25 | 29.35 ± 10.86 | 27.51 ± 7.47 | 0.666 |
Tricuspid valve gradient, mmHg | 28.25 ± 13.68 | 24.18 ± 9.34 | 25.94 ± 9.96 | 0.344 |
SPAP, mmHg | 37.56 ± 16.91 | 32.82 ± 11.52 | 34.02 ± 11.98 | 0.292 |
TC, mmol/L | 3.96 ± 0.91 | 3.44 ± 0.83† | 4.07 ± 1.08 | 0.062 |
TG, mmol/L | 1.08 ± 0.61 | 1.11 ± 1.04 | 1.64 ± 1.01† | 0.001 |
LDL, mmol/L | 2.38 ± 0.61 | 2.08 ± 0.54 | 2.52 ± 0.72 | 0.058 |
HDL, mmol/L | 1.32 ± 0.46 | 1.09 ± 0.28 | 1.13 ± 0.25† | 0.008 |
ALT, U/L | 20.71 ± 14.77 | 16.47 ± 7.85 | 22.26 ± 12.33 | 0.312 |
AST, U/L | 23.93 ± 9.55 | 21.91 ± 6.33 | 21.28 ± 6.88 | 0.206 |
TBIL, µmol/L | 13.94 ± 7.11 | 14.84 ± 8.78 | 14.18 ± 6.11 | 0.889 |
DBIL, µmol/L | 2.87 ± 2.14 | 3.14 ± 2.09 | 2.58 ± 1.28 | 0.515 |
ALB, g/L | 41.39 ± 4.53 | 42.18 ± 4.05 | 41.12 ± 3.29 | 0.662 |
PA, mg/L | 222.73 ± 47.72 | 219.31 ± 43.82 | 235.89 ± 53.33 | 0.278 |
SCr, µmol/L | 59.84 ± 11.07 | 62.62 ± 14.06 | 65.66 ± 18.61† | 0.085 |
GFR, % | 147.09 ± 39.65 | 157.91 ± 39.37 | 135.06 ± 31.25 | 0.060 |
UA, µmol/L | 316.83 ± 71.67 | 331.52 ± 75.52 | 342.62 ± 115.47 | 0.277 |
HGB, g/L | 136.63 ± 25.16 | 141.29 ± 13.96 | 135.08 ± 23.81 | 0.651 |
PLT, 109/L | 224.31 ± 69.37 | 216.71 ± 61.36 | 230.63 ± 59.41 | 0.730 |