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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Deficiency of neuropeptide Y attenuates neointima formation after vascular injury in mice

Fig. 2

Detection of macrophages and VSMCs in the neointima. FeCl3-mediated carotid artery injury was performed in WT and NPY−/− mice. Twenty-one days after the injury, the carotid arteries were excised for immunohistochemical staining. Representative pictures of immunostaining with anti-MOMA-2 antibody (for macrophage, a,b) and anti-a-SMA antibody (for VSMCs, d,e) are depicted. The bar represents 100 μm. MOMA-2-positive neointimal area was significantly reduced (c), and a-SMA-positive neointimal area was increased (f) in the NPY−/− mice compared to that in the WT mice. Values are mean ± SEM (n = 5), *p < 0.05

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