Association between serum 25(OH)D and risk of all-cause mortality in adults with prior cardiovascular disease: a cohort study from NHANES 2007–2018

Table 3 Univariate and multivariate results by cox regression

Exposure	Non-adjusted model HR, 95%CI, P	Minimally-adjusted model HR, 95%CI, P	Fully-adjusted model HR, 95%CI, P
Serum 25(OH)D concentrations (natural log transformation)
Q1 (< 3.22)	1.39 (1.03, 1.88) 0.0302	2.23 (1.63, 3.05) < 0.0001	1.81 (1.31, 2.50) 0.0003
Q2(≥ 3.22, < 3.91)	1.06 (0.87, 1.31) 0.5530	1.51 (1.22, 1.87) 0.0002	1.34 (1.07, 1.66) 0.0091
Q3(≥ 3.91, < 4.31)	1.02 (0.84, 1.24) 0.8207	1.26 (1.03, 1.53) 0.0233	1.28 (1.05, 1.56) 0.0157
Q4(≥ 4.31, < 4.5)	Ref	Ref	Ref
Q5(≥ 4.5)	1.23 (1.00, 1.52) 0.0535	1.16 (0.94, 1.44) 0.1638	1.10 (0.89, 1.37) 0.3826
P for trend	0.2543	0.0014	0.0113

Non-adjusted model: no covariates were adjusted. Minimally-adjusted model: we only adjusted for age, sex; race/ethnicity; education level; family income-poverty ratio. Fully-adjusted model: we adjusted for age, sex, race/ethnicity, education level, smoking status, renal failure, diabetes, hypercholesterolemia, cancer, family history of heart disease, family income-poverty ratio, leisure-time physical activity, BMI, WBC, HDL, TC, Glu, Albumin, Creatinine, Calcium, and Glycohemoglobin

ISSN: 1471-2261