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Table 3 Comparison of the frequency distribution of vital signs, clinical presentations, and laboratory parameters between two groups with and without HD

From: The clinical manifestation and outcome of COVID-19 in patients with a history of ischemic heart disease; a retrospective case-control study

Variable

Without IHD (N = 1218)

With IHD (N = 300)

OR (95% CI)*

P value

Fever

922(75.7%)

195(65%)

0.170(0.34–0.81)

< 0.001

Chill

732(60.1%)

152(50.7%)

0.74(0.45–0.91)

< 0.001

Cough

874(71.8%)

221(73.7%)

1.63(0.83–1.65)

0.198

Sore throat

205(16.8%)

46(15.3%)

0.20(0.11-1.00)

0.827

Loss of smell

162(13.3%)

33(11%)

0.78(0.52–1.45)

0.368

Sneeze

85(7%)

15(5%)

0.65(0.43–1.03)

0.836

Runny nose

124(10.2%)

21(7%)

0.70(0.30–1.07)

0.714

Body pain

689(56.6%)

151(50.3%)

0.64(0.45–1.10)

0.101

Nausea

439(36%)

95(31.7%)

0.84(0.65–1.13)

0.883

Vomiting

285(23.4%)

61(20.3%)

0.80(0.57–1.01)

0.211

Diarrhea

332(27.3%)

59(19.7%)

0.71(0.40–1.01)

0.510

Short of breath

750(61.6%)

187(62.3%)

1.03(0.81–1.61)

0.832

Decreased appetite

535(43.9%)

143(47.7%)

1.28(0.89–1.85)

0.181

Abdominal Pain

190(15.6%)

46(15.3%)

1.01(0.65–1.35)

0.989

Headache

413(33.9%)

84(28%)

0.68(0.87–1.11)

0.155

Chest Pain

299(24.5%)

64(21.3%)

0.71(0.56–1.06)

0.687

Fatigue

724(59.4%)

178(59.3%)

1.00 (0.68–1.36)

0.991

Weight Loss

215(17.7%)

45(15%)

0.83(0.64–1.12)

0.830

Nasal Congestion

48(3.9%)

8(2.7%)

0.65(0.42–1.24)

0.204

Symptom duration

8.23 ± 6.12

7.74 ± 5.67

0.70(0.45–1.12)

0.512

SBP; mmHg

132 ± 22.03

131.58 ± 57.46

1.01(0.68–1.18)

0.800

DBP; mmHg

80.11 ± 35.15

79.1 ± 13.97

1.02(0.60–1.26)

0.555

 h on admission; beat/min

93 ± 15.72

90.02 ± 17.33

0.75(0.46–0.96)

0.003

RR on admission; beat/min

22.42 ± 6.34

22.96 ± 6.04

1.00(0.55–1.11)

0.898

Temperature on admission; °C

37.52 ± 0.99

37.42 ± 2.21

1.01(0.80–1.30)

0.500

SaO2

87.85 ± 27.46

85.1 ± 10.34

0.77(0.09–0.86)

0.026

Laboratory parameters

    

PLT(×103/µL)

192.84 ± 76.34

191.61 ± 77.86

0.99(0.99-1.00)

0.511

WBC(/µL)

6225.22 ± 8618.48

6233.31 ± 3301.1

1.00(1.00-1.01)

0.596

Lymph(/µL)

1199.2 ± 4620.94

1075.4 ± 686.43

0.99(0.96–1.01)

0.385

LDH (U/L)

690.43 ± 586.59

675.59 ± 457

0.99(0.98–1.01)

0.570

AST(U/L)

46.85 ± 39.07

45.53 ± 32.84

1.01(1.00-1.02)

0.083

ALT (U/L)

37.24 ± 40.2

32.7 ± 27.62

0.98(0.97–1.01)

0.128

CRP(mg/l) (0–10 mg/l)

58.21 ± 53.42

56.45 ± 53.45

0.99(0.98–1.01)

0.268

  1. Data shown mean ± SD or N(%)
  2. *: adjusted for age, sex, drugs, comorbidities
  3. OR(95% CI): Odd ratio(95% Confidence interval) SBP: Systolic blood pressure; DBP: Diastolic blood pressure; HR: Heart rate; RR: Respiratory rate; Plt: Platelet; WBC: White blood cell; Lymph: Lymphocyte; LDH: lactate dehydrogenase; AST: Aspartate transaminase; ALT: Alanine transaminase; CRP: C-reactive protein