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Table 2 Echocardiographic measures of systolic and diastolic myocardial function in PB/ELBW compared to controls

From: Myocardial function including estimates of myocardial work in young adults born very preterm or with extremely low birthweight - a cohort study

  

PB/ELBW

 

Controls

P

 

n

 

n

  

EF Teicholz (%), mean (95% CI)

63

61 (59, 62)

64

62 (61, 64)

0.18a

EF Simpson (%), mean (95% CI)

63

59 (58, 61)

64

61 (59, 62)

0.32a

LV-4 C-LS (%), mean (95% CI)

61

-18.7 (-19.2, -18.2)

60

-19.9 (-20.5, -19.4)

0.002a

LV-GLS (%), mean (95% CI)

50

-19.4 (-20.0, -18.9)

53

-20.6 (-21.1, -20.1)

0.003a

GCW (mmHg%), mean (95% CI)

49

1982 (1901, 2063)

51

2074 (1995, 2153)

0.11a

GWW (mmHg%), mean (95% CI)

49

100 (78, 121)

51

92 (71, 113)

0.61a

GWI (mmHg%), mean (95% CI)

49

1749 (1666, 1832)

51

1853 (1772, 1934)

0.08a

GWE (%), mean (95% CI)

49

95 (93, 96)

51

95 (93, 96)

0.85a

IVSDd (cm), mean (95% CI)

63

0.9 (0.8, 0.9)

64

0.9 (0.9, 0.9)

0.08b

PWDd (cm), mean 95% CI)

63

0.8 (0.8, 0.8)

64

0.8 (0.8, 0.9)

1.00b

LVDd (cm), mean (95% CI)

63

4.6 (4.5, 4.7)

64

4.8 (4.7, 4.9)

0.08b

Indexed LV mass (g/m2),

mean (95% CI)

63

69 (65, 73)

64

75 (70, 79)

0.08c

Mitral septal e´(m/s),

mean (95% CI)

61

0.12 (0.11, 0.12)

63

0.12 (0.11, 0.13)

0.99b

Mitral lateral e´ (m/s),

mean (95% CI)

62

0.15 (0.14, 0.16)

64

0.16 (0.13, 0.20)

0.96b

Average mitral E/e´ratio,

mean (95% CI)

61

5.5 (5.3, 5.7)

61

5.4 (5.1, 5.8)

0.82b

Mitral E/A-ratio,

mean (95% CI)

63

1.5 (1.4, 1.6)

61

1.5 (1.4, 1.6)

0.83b

TR peak gradient (mmHg),

mean (95% CI)

37

18 (16, 20)

41

16 (15,18)

0.96b

LA contraction strain (%),

mean (95% CI)

55

-10.5 (-11.5, -9.4)

55

-11.5 (-12.5, -10.3)

0.22a

LA conduit strain (%),

mean (95% CI)

55

27.5 (25.5, 29.5)

55

28.6 (26.6, 30.6)

0.43a

LA reservoir strain (%),

mean (95% CI)

55

38.1 (35.7, 40.5)

55

39.7 (37.4, 42.1)

0.34a

LA volume (ml/m2),

mean (95% CI)

55

21 (19, 22)

55

21 (19, 22)

0.93a

  1. a = ANCOVA adjusted for BSA and transducer difference as appropriate
  2. b= non−parametric two sample Kolmogorov− Smirnov test
  3. c = independent samples t test (with equal variance not assumed)
  4. PB/ELBW: very premature born (< 29 weeks of gestation) or with extremely low birthweight (< 1000 g), EF: ejection fraction, CI: confidence interval, LV: left ventricle, 4 C-LS: 4-chamber longitudinal strain, GLS: global longitudinal strain, GCW: global constructive work, GWW: global wasted work, GWI: global work index, GWE: global work efficiency, IVSDd: intraventricular septum diameter measured in diastole, PWDd: posterior wall diameter measured in diastole, LVDd: left ventricular internal diameter measured in diastole, TR: tricuspid regurgitation, LA: left atrium, ANCOVA: analysis of covariance