Table 3 Univariate and multivariate time-dependent Cox regression analysis for 28-day and 180-day all-cause mortality

28-day Mortality

No hemoglobin drop

Ref.

-

Ref.

-

Ref.

-

Minimal hemoglobin drop

2.38 (1.02–5.55)

0.044

3.44 (1.45–8.18)

0.005

3.44 (1.45–8.20)

0.005

Minor hemoglobin drop

5.09 (1.92–13.48)

0.001

12.90 (4.51–36.92)

< 0.001

14.31 (4.99–41.06)

< 0.001

Major hemoglobin drop

3.30 (1.07–10.20)

0.038

15.81 (4.42–56.56)

< 0.001

16.15 (4.47–58.32)

< 0.001

Continuous hemoglobin drop

1.24 (1.14–1.34)

< 0.001

1.60 (1.38–1.86)

< 0.001

1.58 (1.37–1.84)

< 0.001

180-day Mortality

No hemoglobin drop

Ref.

-

Ref.

-

Ref.

-

Minimal hemoglobin drop

1.75 (0.88–3.49)

0.113

2.75 (1.35–5.60)

0.005

2.75 (1.35–5.60)

0.005

Minor hemoglobin drop

3.83 (1.67–8.79)

0.002

11.79 (4.76–29.10)

< 0.001

12.68 (5.13–31.33)

< 0.001

Major hemoglobin drop

2.40 (0.89–6.41)

0.082

13.90 (4.52–42.73)

< 0.001

13.87 (4.50-42.76)

< 0.001

Continuous hemoglobin drop

1.22 (1.14–1.30)

< 0.001

1.61 (1.40–1.85)

< 0.001

1.34 (1.22–1.47)

< 0.001