Table 3 Interaction of age and stage of hypertension on cardiovascular mortality and all-cause mortality

male

60–69

stage 1

1(reference)

1(reference)

1(reference)

1(reference)

60–69

stage 2

1.01(0.92–1.10)

1.01(0.88–1.14)

0.98(0.93–1.04)

1.00(0.95–1.06)

60–69

stage 3

1.55(1.40–1.71)

1.75(1.52–2.01)

1.25(1.17–1.33)

1.28(1.20–1.36)

70–85

stage 1

4.43(4.11–4.77)

4.80(4.37–5.26)

3.72(3.55–3.89)

3.54(3.38–3.72)

70–85

stage 2

4.67(4.31–5.06)

5.05(4.59–5.56)

3.77(3.58–3.97)

3.63(3.44–3.82)

70–85

stage 3

5.56(5.06–6.11)

6.39(5.75–7.10)

4.19(3.93–4.46)

4.06(3.81–4.33)

female

60–69

stage 1

1(reference)

1(reference)

1(reference)

1(reference)

60–69

stage 2

1.09(0.98–1.20)

1.10(1.00-1.22)

1.03(0.96–1.09)

1.04(0.98–1.11)

60–69

stage 3

1.44(1.28–1.62)

1.48(1.31–1.66)

1.26(1.17–1.36)

1.28(1.19–1.39)

70–85

stage 1

6.47(6.02–6.96)

5.89(5.47–6.34)

4.74(4.52–4.98)

4.36(4.15–4.58)

70–85

stage 2

6.42(5.94–6.95)

5.87(5.42–6.35)

4.50(4.26–4.75)

4.14(3.92–4.37)

70–85

stage 3

7.56(6.89–8.29)

7.03(6.41–7.72)

5.08(4.75–5.43)

4.73(4.43–5.06)

Interaction on multiplicative scale

HR ^a

HR ^b

HR ^a

HR ^b

male

70–85*stage 2

1.06(0.94–1.18)

1.05(0.93–1.17)

1.03(0.96–1.11)

1.02(0.95–1.10)

70–85*stage 3

0.82(0.72–0.93)

0.81(0.71–0.93)

0.91(0.83–0.99)

0.90(0.82–0.98)

female

70–85*stage 2

0.91(0.81–1.03)

0.90(0.80–1.02)

0.92(0.85-1.00)

0.91(0.84–0.99)

70–85*stage 3

0.81(0.70–0.94)

0.81(0.70–0.93)

0.85(0.77–0.94)

0.85(0.77–0.93)

Interaction on additive scale

RERI ^a

RERI ^b

RERI ^a

RERI ^b

male

70–85*stage 2

0.23(-0.12-0.59)

0.23(-0.11-0.57)

0.07(-0.12-0.26)

0.08(-0.11-0.26)

70–85*stage 3

0.61(0.10–1.12)

0.58(0.09–1.07)

0.23(-0.04-0.49)

0.24(-0.02-0.50)

female

70–85*stage 2

-0.13(-0.56-0.29)

-0.13(-0.52-0.26)

-0.27(-0.50–0.04)

-0.26(-0.48–0.05)

70–85*stage 3

0.65(0.04–1.25)

0.66(0.10–1.23)

0.07(-0.25-0.39)

0.09(-0.21-0.39)