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Table 2 Receiver operating characteristics

From: Speckle-tracking echocardiography provides sensitive measurements of subtle early alterations associated with cardiac dysfunction in T2DM rats

Parameter

AUC (95% CI)

z statistic

P value

Optimal cut off

Sensitivity (95% CI)

Specificity (95% CI)

EF

0.979 (0.821 to 1.00)

20.39

 < 0.001***

65.62(%)

100.00 (73.5—100.0)

91.67 (61.5—99.8)

FS

0.979 (0.821 to 1.00)

22.66

 < 0.001***

35.07(%)

83.33 (51.6—97.9)

100.00 (73.5—100.0)

CO

0.639 (0.419 to 0.823)

1.17

0.243

89.75(ml/min)

75.00 (42.8—94.5)

58.33 27.7—84.8

SV

0.549 (0.334 to 0.750)

0.39

0.695

247.47(μl)

83.33 (51.6—97.9)

41.67 (15.2—72.3)

MV E/A

0.847 (0.643 to 0.960)

4.24

 < 0.001***

1.25

83.33 (51.6—97.9)

83.33 (51.6—97.9)

FAC

0.927 (0.744 to 0.993)

6.40

 < 0.001***

48(%)

83.33 (51.6—97.9)

100.00 (73.5—100.0)

GLS

0.681 (0.461 to 0.854)

1.48

0.138

-10.83(%)

58.33 (27.7—84.8)

91.67 (61.5—99.8)

GLSR

0.799 (0.586 to 0.933)

3.18

0.002**

-3.22(1/s)

100.00 73.5—100.0

58.33 (27.7—84.8)

GCS

0.819 (0.610 to 0.945)

3.53

 < 0.001***

-17.14(%)

91.67 (61.5—99.8)

66.67 (34.9—90.1)

GCSR

0.899 (0.707 to 0.984)

6.34

 < 0.001***

-4.03(1/s)

100.00 (73.5—100.0)

66.67 34.9—90.1

GRS

0.528 (0.316 to 0.733)

0.22

0.828

27.66(%)

33.33 (9.9—65.1)

91.67 (61.5—99.8)

GRSR

0.740 (0.522 to 0.895)

2.30

0.022*

4.93(1/s)

83.33 (51.6—97.9)

58.33 (27.7—84.8)

  1. AUC area under the ROC curve, CI confidence interval, EF ejection fraction, FS fractional shortening, CO cardiac output, SV stroke volume, MV E/A mitral valve E/A, FAC fractional area change, GLS global longitudinal strain, GLSR global longitudinal strain rate, GCS global circumferential strain, GCSR global circumferential strain rate, GRS global radial strain, GRSR global radial strain rate. ROC analysis was applied to conventional parameters and STE parameters, respectively
  2. *P < 0.05
  3. **P < 0.01
  4. ***P < 0.001 vs AUC of 0.5