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Table 1 Baseline characteristics between the training group and the validation group

From: A nomogram based on endothelial function and conventional risk factors predicts coronary artery disease in hypertensives

Variables

Training group

(n = 1204)

Validation group

(n = 548)

P value

With CAD

263 (21.8%)

76 (13.9%)

 

Age, yearsa

61.7 ± 12.5

60.6 ± 13.4

0.120

Maleb

695 (57.7%)

295 (53.8%)

0.128

Waist circumference, cma

87.9 ± 9.4

87.2 ± 8.4

0.119

Duration of EH, yearsc

2.0 [1.0,10.0]

4.0 [0.0,10.0]

0.563

Smokingb

166 (13.8%)

61 (11.1%)

0.125

Family history of cardiovascular diseaseb

219 (18.2%)

103 (18.8%)

0.761

EH treatmentb

508(42.2%)

272 (49.6%)

0.004*

Urbanb

505 (41.9%)

252 (46.0%)

0.113

Systolic blood pressure, mmHga

135.8 ± 15.0

134.7 ± 17.9

0.212

Diastolic blood pressure, mmHga

79.9 ± 11.0

80.8 ± 11.1

0.105

Diabetes mellitusb

152 (12.6%)

63 (11.5%)

0.505

Biochemical indicators

   

 White blood cells, 109/La

6.0 ± 1.7

6.0 ± 1.5

0.891

 Total bilirubin, umol/La

13.9 ± 5.4

13.8 ± 5.4

0.696

 AST, U/La

26.5 ± 9.5

25.1 ± 7.4

0.001*

 Creatinine, umol/La

72.9 ± 19.0

66.1 ± 16.2

< 0.001*

 Glucose, mmol/La

5.8 ± 1.3

5.8 ± 1.3

0.464

 Uric acid, mmol/La

348.7 ± 94.7

353.8 ± 87.8

0.362

 Total cholesterol, mmol/La

5.0 ± 1.1

4.8 ± 1.2

< 0.001*

 Triglyceride, mmol/Lc

2.0 [1.0,10.0]

1.3 [0.9,1.8]

0.068

 LDL-C, mmol/La

3.0 ± 1.0

3.0 ± 1.0

0.358

 HDL-C, mmol/La

1.4 ± 0.4

1.4 ± 0.5

0.079

 FMD (%)a

9.4 ± 5.8

9.9 ± 5.5

0.088

  1. EH, essential hypertension; CAD, coronary artery disease; AST, aspartate aminotransferase; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; FMD, flow-mediated dilation
  2. *P < 0.05, acompared by independent sample t-test, bcompared by Person chi square test, ccompared by Mann Whitney U-test