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Fig. 5 | BMC Cardiovascular Disorders

Fig. 5

From: HiPSC-derived cardiomyocyte to model Brugada syndrome: both asymptomatic and symptomatic mutation carriers reveal increased arrhythmogenicity

Fig. 5

Simultaneous recording of action potential (AP) and contraction of same cells. (A) AP (upper panel) and corresponding beating traces (lower panel) recorded from same cells from WT (a,b), asymptomatic (c,d), and symptomatic (e,f) CMs. (B) Image of patch-clamp recording of CM where green rectangle represents the user-selected contraction region of interest. (C-D) Comparison of half-width contraction and relaxation durations measured from WT, asymptomatic, and symptomatic CMs. Numbers in parenthesis represent the number of cells used. Data are presented as mean ± S.E.M.

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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