Table 2 Changes in plaque stratified by liraglutide treatment
Lira + (n = 55) | Lira - (n = 149) | P value | |
|---|---|---|---|
Total atheroma volume (mm3) | |||
- Baseline | 599.4 ± 340.6 | 671.2 ± 358.8 | 0.200 |
- Follow-up | 637.5 ± 386.6 | 669.9 ± 369.3 | 0.583 |
- Difference | 38.0 ± 180.3 | -1.3 ± 159.7 | 0.134 |
Dense calcium plaque volume (mm3) | |||
- Baseline | 37.7 IQR (5.8–89.6) | 40.0 IQR (4.5–114.3) | 0.956 |
- Follow-up | 41.9 IQR (5.0–139.9) | 47.7 IQR (6.0–141.0) | 1.000 |
- Difference | 6.7 IQR (0–26.3) | 7.3 IQR (0–23.5) | 0.959 |
Fibrous plaque volume (mm3) | |||
- Baseline | 346.5 ± 198.4 | 405.8 ± 211.2 | 0.072 |
- Follow-up | 380.6 ± 248.4 | 403.4 ± 218.5 | 0.524 |
- Difference | 34.1 ± 128.7 | -2.4 ± 101.0 | 0.035 |
Fibrous fatty plaque volume (mm3) | |||
- Baseline | 98.0 ± 62.7 | 113.2 ± 77.3 | 0.192 |
- Follow-up | 97.0 ± 60.7 | 110.0 ± 79.5 | 0.272 |
- Difference | -1.0 ± 45.4 | -3.2 ± 40.3 | 0.739 |
Necrotic core plaque volume (mm3) | |||
- Baseline | 59.7 ± 72.2 | 58.9 ± 75.7 | 0.949 |
- Follow-up | 45.4 ± 50.0 | 49.5 ± 65.1 | 0.675 |
- Difference | -13.8 ± 69.0 | -9.8 ± 61.4 | 0.695 |