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Table 5 Univariate and multivariate Cox analyses among the hypertension patients

From: AT1R gene rs389566 polymorphism contributes to MACCEs in hypertension patients

Risk factors

Univariate cox regress

 

Multivariate cox regress

OR (95% CI) P Value

OR (95% CI) P Value

rs389566 AA + AT/TT

1.731 (1.138–2.635)

0.010

 

1.770(1.148–2.729)

0.010

CAD

4.912 (3.128–7.714)

< 0.001

 

4.118(2.542–6.672)

< 0.001

Age

1.041(1.023–1.060)

< 0.001

 

1.028(1.009–1.047)

0.003

Gender

0.789 (0.545–1.142)

0.208

 

-

-

BMI

0.951(0.890–1.016)

0.136

 

-

-

SBP

0.992 (0.982–1.002)

0.135

 

-

-

DBP

0.992(0.977–1.007)

0.278

 

-

-

Glucose

1.107(1.060–1.156)

< 0.001

 

1.036(0.985–1.089)

0.167

TG

1.008(0.897–1.132)

0.895

 

-

-

TC

1.101(0.930–1.303)

0.264

 

-

-

HDL-c

0.578(0.297–1.127)

0.108

 

-

-

LDL-c

1.108(0.900-1.363)

0.334

 

-

-

  1. BMI: Body mass index, SBP: Systolic blood pressure, DBP: Diastolic blood pressure, TG: Triglycerides, TC: Total Cholesterol,
  2. HDL-c: High density lipoprotein cholesterol, LDL-c: Low density lipoprotein cholesterol, MACCEs: major adverse cardiovascular
  3. events. CAD: Coronary heart disease, OR: Odds ratio, CI: Confidence Interval, P < 0.05 was considered significant difference