Skip to main content

Table 3 Comparison of general characteristics in patients with hypertension according to different ages

From: AT1R gene rs389566 polymorphism contributes to MACCEs in hypertension patients

Characteristics

< 40 years old

(n = 20)

41–50 years old

(n = 178)

51–60 years old

(n = 218)

> 60 years old

(n = 293)

P Value

Gender, n (%)

     

Male

18(90.0%)

139(77.7%)

123(56.2%)

127(42.8%)

< 0.001

Female

2(10.0%)

40(22.3%)

96(43.8%)

170(57.2%)

Smoking, n (%)

     

No

7(35.0%)

83(46.4%)

146(66.7%)

235(79.1%)

< 0.001

Yes

13(65.0%)

96(53.6%)

73(33.3%)

62(20.9%)

Alcohol intake, n (%)

    

No

9(1.7%)

104(19.5%)

164(30.8%)

256(48.0%)

< 0.001

Yes

11(55.0%)

75(41.9%)

55(25.1%)

41(13.8%)

T2DM

     

No

17(85.0%)

155(86.6%)

171(78.1%)

207(69.7%)

< 0.001

Yes

3(15.0%)

24(13.4%)

48(21.9%)

90(30.3%)

CAD

     

No

15(75.0%)

101(56.4%)

107(48.9%)

118(39.7%)

< 0.001

Yes

5(25.0%)

78(43.6%)

112(51.1%)

179(60.3%)

SBP (mmHg)

137 ± 16

129 ± 17

129 ± 16

132 ± 20

0.039

DBP (mmHg)

87 ± 14

82 ± 12

80 ± 11

77 ± 13

< 0.001

BMI (kg/m2)

29.34 ± 3.52

27.03 ± 2.91

26.60 ± 3.61

25.63 ± 3.34

< 0.001

Glucose(mmol/L)

6.16 ± 2.06

7.06 ± 3.27

6.30 ± 2.63

7.76 ± 3.58

< 0.001

TG (mmol/L)

2.68 ± 3.04

2.36 ± 1.84

2.00 ± 1.73

1.84 ± 1.20

0.004

TC (mmol/L)

4.72 ± 1.17

4.37 ± 1.07

4.31 ± 1.15

4.26 ± 1.11

0.311

HDL–c (mmol/L)

1.02 ± 0.25

0.96 ± 0.23

1.04 ± 0.31

1.08 ± 0.30

0.001

LDL–c (mmol/L)

3.12 ± 0.79

2.74 ± 0.90

2.68 ± 0.87

2.62 ± 0.93

0.096

MACCEs, n (%)

1 (0.9%)

15 (12.8%)

37 (31.6%)

64 (54.7%)

0.001

RS389566 TT,

n (%)

13 (2.8%)

116 (25.1%)

133 (28.7%)

201 (43.4%)

0.446

RS16860760 AA + AG, GG

n (%)

20 (2.8%)

179 (25%)

219 (30.6%)

297 (41.5%)

0.932

  1. BMI: Body mass index, SBP: Systolic blood pressure, DBP: Diastolic blood pressure, TG: Triglycerides, TC: Total Cholesterol, HDL-c: High density lipoprotein cholesterol, LDL-c: Low density lipoprotein cholesterol, MACCEs: major adverse cardiovascular events. P < 0.05 was considered significant difference