Table 1 Patient comorbidity profile by cohort
Cohort | Class 1–3 obesity | Diabetes | Symptoms and signs involving the circulatory and respiratory systems | Hypertensive diseases | Disorders of lipoprotein metabolism and other lipidemias | Other forms of heart disease | Gastro oesophageal reflux disease | Abnormal findings on examination of blood without diagnosis |
|---|---|---|---|---|---|---|---|---|
Cohort 1 (low pre-test risk, CAD diagnosis within 3 months of index test) | 43% | 20% | 83% | 66% | 59% | 45% | 33% | 29% |
Cohort 2 (low pre-test risk, no CAD diagnosis following index test) | 43% | 14% | 87% | 56% | 51% | 39% | 33% | 28% |
Cohort 3 (high pre-test risk, CAD diagnosis within 3 months of index test) | 60% | 51% | 88% | 92% | 85% | 50% | 40% | 39% |
Cohort 4 (high pre-test risk, no CAD diagnosis following index test) | 61% | 46% | 89% | 89% | 82% | 43% | 42% | 39% |
Cohort 5 (existing CAD diagnosis, no prior cardiac events) | 52% | 44% | 88% | 92% | 89% | 64% | 42% | 36% |
Cohort 6 (existing CAD diagnosis, prior cardiac event within 1 year) | 52% | 54% | 97% | 96% | 91% | 82% | 48% | 49% |
Cohort 7 (existing CAD diagnosis, prior cardiac event within 1–2 years) | 52% | 51% | 96% | 96% | 93% | 80% | 46% | 44% |
Cohort 8 (low pre-test risk, subsequent CAD diagnosis more than 3 months after index test) | 42% | 22% | 88% | 92% | 89% | 64% | 42% | 36% |
Cohort 9 (high pre-test risk, subsequent CAD diagnosis more than 3 months after index test) | 60% | 51% | 97% | 96% | 91% | 82% | 48% | 49% |