Outcome | NOACs | Warfarin | Hazard Ratio (95% CI) | P value | ||
---|---|---|---|---|---|---|
no. of patients with event | no. of 100 patient-years | no. of patients with event | no. of 100 patient-years | |||
Net adverse clinical event | 34 | 25.6 | 52 | 32.8 | 0.74 (0.48–1.14) | 0.172 |
Ischemic stroke or systemic embolism | 7 | 4.9 | 2 | 1.1 | 3.53 (0.78–16.13) | 0.102 |
Major bleeding | 29 | 21.3 | 51 | 32.0 | 0.63 (0.40-1.00) | 0.0499 |
ICH | 11 | 7.7 | 21 | 12.2 | 0.59 (0.28–1.22) | 0.155 |
GI bleeding | 12 | 8.4 | 19 | 11.0 | 0.72 (0.35–1.49) | 0.381 |
All Cause death | 100 | 67.8 | 98 | 54.8 | 1.15 (0.87–1.53) | 0.323 |