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Fig. 5 | BMC Cardiovascular Disorders

Fig. 5

From: Integrative analysis of HASMCs gene expression profile revealed the role of thrombin in the pathogenesis of atherosclerosis

Fig. 5

A The network generated by ClueGo and Cluepedia shows the pathways of KEGG enrichment and the genes shared between them. B The PPI network of DEGs, which was based on String, consisted of 46 nodes and 123 edges. Different node colors represent up-regulated and down-regulated DEGs, while the edge color mapping represents the combined score. A sub-cluster of 10 genes, which is shown in the center of the network, is detected by MCODE(MCODE score ≥ 8). C Cytohubba identified the top 10 genes in the PPI network, ranked by node degree. D Based on the intersection of Cytohubba and MCODE, we identified 9 up-regulated genes as hub genes

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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