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Table 2 Participant characteristics, baseline: Multi-Ethnic Study of Atherosclerosis, 2000 to 2002

From: Associations of emotional social support, depressive symptoms, chronic stress, and anxiety with hard cardiovascular disease events in the United States: the multi-ethnic study of atherosclerosis (MESA)

 

All participant

HCVD

No HCVD

P. value*

N total

6779

370

6409

N (%)

    

Age

62.2 ± 10.2

68.0 ± 9.7

61.8 ± 10.2

< 0.001

Gender

    

Male

3197(47.2)

220(59.5)

2977(46.5)

< 0.001

Female

3582(52.8)

150(40.5)

3432(53.5)

 

Education

    

Less than diploma

1215(17.0)

85(23.0)

1130(17.7)

< 0.001

Diploma or some college

2814(41.6)

169(45.8)

2645(41.4)

 

College degree or higher

2729(40.4)

115(31.2)

2614(40.9)

 

Race

    

Caucasian -Americans

2614(38.6)

156(42.2)

2458(38.3)

0.003

Chinese -Americans

801(11.8)

22(5.9)

779(12.2)

 

African -American

1879(27.7)

102(27.6)

1777(27.7)

 

Hispanic -Americans

1485(22.9)

90(24.3)

1395(21.8)

 

Alcohol status

    

Never

1382(20.5)

74(20.1)

1308(20.6)

0.004

Former

1609(23.9)

114(31.0)

1495(23.5)

 

Current

3739(55.6)

180(48.9)

3559(55.9)

 

Smoking status

    

Never

3400(50.3)

172(46.6)

3228(50.5)

0.003

Former

2475(36.6)

127(34.4)

2348(36.7)

 

Current

884(13.1)

70(19.0)

814(12.8)

 

Diabetes

    

Normal

4972(73.6)

226(61.3)

4746(74.3)

< 0.001

Impaired fasting glucose

933(13.8)

54(14.6)

879(13.8)

 

Untreated diabetes mellitus

179(2.6)

10(2.7)

169(2.6)

 

Treated diabetes mellitus

671(10.0)

79(21.4)

5928(9.3)

 

Current aspirin use(at least 3 days/wk)

    

No

5202(80.0)

270(76.5)

4932(80.3)

0.07

Yes

1201(20.0)

83(23.5)

1208(19.7)

 

Hypertension medication use

    

No

4250(62.7)

175(47.4)

4075(63.60)

< 0.001

Yes

2526(37.3)

194(52.6)

2332(36.4)

 

Family history of heart attack

    

No

3639(57.3)

162(47.2)

3477(57.8)

< 0.001

Yes

2722(42.8)

181(52.8)

2541(42.2)

 

Mean(SD)

    

Age, y

62.2(10.2)

68.0(9.7)

61.8(10.2)

< 0.001

Height, cm

166.4(10.0)

166.6(10.4)

166.3(9.9)

0.32

Total intentional exercise (MET-min/wk)

1556.2(2344.0)

1260.7(1808.8)

1573.2(2370.2)

0.006

LDL-C, mg/dl

117.2(31.5)

118.7(31.7)

117.1(31.5)

0.34

HDL-C, mg/dl

51.0(14.8)

47.4(13.7)

51.2(14.9)

< 0.001

Systolic blood pressure, mmHg

126.6(21.5)

137.8(23.0)

125.9(21.2)

< 0.001

Triglycerides, mg/dl

131.5(88.8)

143.6(81.4)

130.8(89.2)

< 0.001

BMI,Kg/m2

28.3(5.4)

28.6(5.1)

28.3(5.4)

0.17

 C-Reactive Protein, mg/L

3.8(5.8)

4.3(6.0)

3.7(5.8)

0.03

Fibrinogen, mg/dL

346.7(73.9)

369.4(82.5)

345.4(73.2)

< 0.001

Interleukine-6

1.6(1.2)

1.9(1.4)

1.5(1.2)

< 0.001

Psychosocial factor

    

CES-D (Range,0–60)

7.6(7.6)

8.1(8.1)

7.5(7.5)

0.06

CBS (Range,0–5)

1.2(1.2)

1.3(1.2)

1.2(1.2)

0.15

ESS (Range,6–30)

24.1(5.2)

23.8(5.5)

24.2(5.3)

0.36

Anxiety (Range,10–40)

15.9(4.5)

15.8(4.6)

15.9(4.5)

0.62

  1. BMI indicates body mass index; HDL-c, high-density lipoprotein- cholesterol; CES-D, Center for Epidemiologic Studies Depression Scale; MET, metabolic equivalent of task; LDL-c, high-density lipoprotein-cholesterol; SBP, systolic blood pressure; and CVD, cardiovascular disease; CBS, Chronic Burden Scale; ESS, Emotional Social Support
  2. *P values from t tests or χ2 tests or, as appropriate, are for comparisons of those who did or did not experience a CVD during follow-up