Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation

Table 3 Clinical and biological variables of the two groups prior to treatment

Variable	HD	HDF	t/χ²	p
Subject number	16	16
Males, n (%)	11 (68.8%)	9 (56.3%)	0.533	0.465
Age (years)	60.37 ± 9.25	59.06 ± 9.82	0.389	0.700
Dialysis vintage (years)	4.18 ± 1.64	3.43 ± 1.63	1.296	0.205
Kt/V	1.45 ± 0.11	1.43 ± 0.10	0.418	0.679
BUN (mmol/L)	24.76 ± 6.36	24.24 ± 5.19	0.252	0.803
SCr (µmol/L)	964.83 ± 161.13	942.25 ± 181.24	0.584	0.712
Pre-treatment plasma MtDNA (10⁵ copies/mL)	4.47 ± 1.88	4.85 ± 1.55	− 0.618	0.542

HD: Hemodialysis; HDF: hemodiafiltration; Kt/V: formula for dialysis efficiency; BUN: blood urea nitrogen; SCr: serum creatinine; MtDNA: mitochondrial DNA

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