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Table 2 Plasma MtDNA is linked to CVD risk in MHD patients

From: Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation

Variable

Low plasma MtDNA

High plasma MtDNA

t

p

Subject number

21

21

  

Hs-CRP (mg/L)

3.73 ± 1.89

5.02 ± 2.06

− 2.104

0.042

MCP-1 (pg/mL)

64.72 ± 42.27

99.97 ± 39.63

− 2.788

0.008

Fibrinogen (g/L)

2.61 ± 0.32

2.56 ± 0.35

0.476

0.637

ESR (mm/hour)

17.26 ± 6.54

19.37 ± 6.92

− 1.012

0.317

FRS

16.52 ± 6.39

21.80 ± 7.18

− 2.520

0.016

  1. MtDNA: Mitochondrial DNA; Hs-CRP: high-sensitive C-reactive protein; MCP-1: monocyte chemoattractant protein-1; ESR: erythrocyte sedimentation rate; FRS: framingham risk score