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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation

Fig. 2

HCMECs internalize extracellular MtDNA in the uremic milieu. A PCR analysis of cytochrome B abundance in cytosolic fractions. The internal reference was 18S rDNA. B PCR analysis was performed on TLR9, in which GAPDH was taken as internal reference. Each experiment was performed in triplicate and repeated for three times. *p < 0.05 compared to normal serum group; #p < 0.05 compared to uremic serum group. Data are mean ± SD. NS, normal serum; US, uremic serum

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