Table 1 Baselines characteristics of patients with an index-hospitalization due to STEMI in 2010 to 2017
No CKD | CKD Stage 1 | CKD Stage 2 | CKD Stage 3 | CKD Stage 4 | CKD Stage 5 | CKD Stage 5D | p value | |
|---|---|---|---|---|---|---|---|---|
Patients, n (%) | 137,682 (78.6) | 1480 (0.8) | 8347 (4.8) | 20,458 (11.7) | 4960 (2.8) | 1295 (0.7) | 965 (0.6) | |
Female sex, n (%) | 44,715 (32.5) | 556 (37.6) | 3258 (39.0) | 9806 (47.9) | 2767 (55.8) | 511 (39.5) | 334 (34.6) | < 0.001 |
Median age, yrs (IQR) | 65 (21) | 73 (18) | 75 (16) | 79 (12) | 81 (11) | 76 (14) | 72 (18) | < 0.001 |
Concomitant diseases recorded by ICD codes up to two years before STEMI | ||||||||
Coronary artery disease, n (%) | 61,756 (44.9) | 970 (65.5) | 5139 (61.6) | 13,013 (63.6) | 3119 (62.9) | 815 (62.9) | 760 (78.8) | < 0.001 |
Hypertension, n (%) | 114,014 (82.8) | 1414 (95.5) | 7,825 (93.7) | 19,747 (96.5) | 4834 (97.5) | 1255 (96.9) | * | < 0.001 |
Diabetes mellitus, n (%) | 45,691 (33.2) | 926 (62.6) | 4478 (53.6) | 12,136 (59.3) | 3208 (64.7) | 856 (66.1) | 628 (65.1) | < 0.001 |
Dyslipidemia, n (%) | 98,882 (71.8) | 1218 (82.3) | 6514 (78.0) | 15,745 (77.0) | 3673 (74.1) | 992 (76.6) | 765 (79.3) | < 0.001 |
Obesity, n (%) | 32,454 (23.6) | 556 (37.6) | 2820 (33.8) | 6832 (33.4) | 1690 (34.1) | 485 (37.5) | 333 (34.5) | < 0.001 |
Nicotine abuse, n (%) | 37,826 (27.5) | 325 (22.0) | 1665 (19.9) | 2777 (13.6) | 563 (11.4) | 207 (16.0) | 203 (21.0) | < 0.001 |
Atrial fibrillation/flutter, n (%) | 21,509 (15.6) | 389 (26.3) | 2365 (28.3) | 7592 (37.1) | 2082 (42.0) | 543 (41.9) | 437 (45.3) | < 0.001 |
Chronic heart failure, n (%) | 56,644 (41.1) | 918 (62.0) | 5469 (65.5) | 14,784 (72.3) | 3959 (79.8) | 1025 (79.2) | 737 (76.4) | < 0.001 |
Right heart failure, n (%) | 8428 (6.1) | 197 (13.3) | 1194 (14.3) | 4503 (22.0) | 1467 (29.6) | 393 (30.3) | 252 (26.1) | < 0.001 |
Left heart failure, n (%) | < 0.001 | |||||||
None | 89,984 (65.4) | 695 (47.0) | 3572 (42.8) | 7699 (37.6) | 1532 (30.9) | * | 322 (33.4) | |
NYHA 1 | 4232 (3.1) | 56 (3.8) | 261 (3.1) | 443 (2.2) | 56 (1.1) | * | 18 (1.9) | |
NYHA 2 | 11,250 (8.2) | 145 (9.8) | 1077 (12.9) | 1829 (8.9) | 266 (5.8) | * | 74 (7.7) | |
NYHA 3 | 13,813 (10.0) | 240 (16.2) | 1458 (17.5) | 3692 (18.0) | 837 (16.9) | * | 185 (19.2) | |
NYHA 4 | 18,403 (13.4) | 344 (23.2) | 1979 (23.7) | 6795 (33.2) | 2249 (45.3) | * | 366 (37.9) | |
Lower extremity artery disease, n (%) | < 0.001 | |||||||
No LEAD | 128,741 (93.5) | 1299 (87.8) | 7182 (86.0) | 17,117 (83.7) | 3993 (80.5) | 965 (74.5) | 597 (61.9) | |
LEAD 1-3 | 8010 (5.8) | 155 (10.5) | 996 (11.9) | 2791 (13.6) | 789 (15.9) | 257 (19.8) | 263 (27.3) | |
LEAD 4–6 | 931 (0.7) | 26 (1.8) | 169 (2.0) | 550 (2.7) | 178 (3.6) | 73 (5.6) | 105 (10.9) | |
Cancer, n (%) | 19,027 (13.8) | 305 (20.6) | 1807 (21.6) | 5096 (24.9) | 1220 (24.6) | 324 (25.0) | 249 (25.8) | < 0.001 |
Previous events and interventions recorded by ICD codes and OPS-codes up to two years before STEMI | ||||||||
Previous cerebrovascular disease, n (%) | 10,706 (7.8) | 209 (14.1) | 1201 (14.4) | 3438 (16.8) | 876 (17.7) | 213 (16.4) | 245 (25.4) | < 0.001 |
Previous stroke, n (%) | 10,221 (7.4) | 209 (14.1) | 1231 (14.7) | 3880 (19.0) | 1025 (20.7) | 227 (17.5) | 237 (24.6) | < 0.001 |
Previous myocardial infarction, n (%) | 11,152 (8.1) | 200 (13.5) | 1062 (12.7) | 2811 (13.7) | 687 (13.9) | 191 (14.7) | 240 (24.9) | < 0.001 |
Previous percutaneous coronary intervention, n (%) | 3668 (2.7) | 79 (5.3) | 573 (6.9) | 1380 (6.7) | 265 (5.3) | 104 (8.0) | 189 (19.6) | < 0.001 |
Previous coronary artery bypass grafting, n (%) | 3945 (2.9) | 108 (7.3) | 573 (6.9) | 1647 (8.1) | 389 (7.8) | 144 (11.1) | 149 (15.4) | < 0.001 |
Previous valve replacement, n (%) | 464 (0.3) | 11 (0.7) | 91 (1.1) | 281 (1.4) | 61 (1.2) | 14 (1.1) | 42 (4.4) | < 0.001 |