Table 2 Characteristics of patients with Addison’s disease complicated by cardiovascular disease
From: Coronary artery disease in a patient with Addison’s disease: a case report and literature review
Resource | Gender | Age (year) | Etiology of API | ACTH | Cortisol | Symptom (s) | ECG | Myocardial enzyme | Angiography | Echocardiography | Cardiac diagnosis |
|---|---|---|---|---|---|---|---|---|---|---|---|
Current case | M | 51 | Adrenal tuberculosis | ↑ | ↓ | Chest pain at rest | (–) | (–) | Proximal right coronary artery 80%, proximal circumflex artery 40%, middle of the anterior descending branch 30% | (–) | Angina pectoris |
Iga. et al. [18] | F | 74 | Adrenal crisis induced by operation | ↓ | ↓ | Fatigue, loss of appetite | Deep negative T wave | (–) | (–) | Akinesis of antero-septal and LV apical area | Myocardial hibernation or stunning |
F | 64 | Adrenal crisis induced by hypoglycemia | ↓ | ↓ | Loss of consciousness | ST elevation in the left precordial leads | (–) | (–) | Aneurysm in the antero-septal and apical region of LV | Myocardial hibernation or stunning | |
Ozcan. et al. [19] | F | 39 | NK | ↑ | ↓ | Nausea, vomiting, weakness, and hyperpigmentation | ST depression and inverted T wave on inferior and V4–V6 | (–) | (–) | (–) | ECG changes caused by adrenal crisis |
Akpa. et al. [20] | M | 48 | Adrenal tuberculosis | ↑ | ↓ | Chest pain, nausea, vomiting, and difficulty breathing | Low voltage, ST elevation of 1.5 mm in all chest leads | Slight elevation of LDH, normal CPK | Not complete | Not complete | Angina pectoris |
Punnam. et al. [21] | F | 71 | NK | – | – | Weakness, fatigue, and lightheadedness | ST elevation in V2–V6 | ↑ | (–) | Dyskinetic apical and inferior walls, EF25-30% | Takotsubo cardiomyopathy induced by Adrenal crisis |
Barcin. et al. [22] | F | 41 | NK | – | – | Chest pain | (–) | ↑ | (–) | LV apical akinesis, EF 44% | Takotsubo cardiomyopathy |
Singh. et al. [23] | M | 48 | Pituitary adenoma | ↓ | ↓ | Difficulty breathing, vomiting | ST elevation and T wave inverted in the lateral leads | ↑ | (–) | RWMAs involving left anterior descending territory, low EF | Takotsubo cardiomyopathy |
Campean. et al. [24] | F | 41 | II -APS | ↓ | ↓ | Shortness of breath | Tachycardia, inverted T wave in V5, V6, prolongation of cQT | ↑ | Not complete | Dyskinetic apical lateral and inferior walls of LV, EF 30% | Takotsubo cardiomyopathy |
Maranduca. et al. [17] | F | 71 | Possible adrenal tuberculosis | ↑ | ↓ | Chest pain | q wave in I, aVL, V5, V6, ST elevation in V2–V5 | (–) | Not complete | LV apical and inferior wall akinesis EF 50% | STEMI |
Otsuka. et al. [25] | M | 60 | Adrenalectomy | ↑ | ↓ | Palpitation, fatigue, chest pain | ST elevation, ventricular tachycardia | (–) | No significant visible stenosis, diffuse spasm of LAD after ergometrine administration | (–) | Coronary spasms |