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Table 5 Effect of P2Y1 and P2Y12 genotypes on MAR in response to 5 μmol/L ADP among healthy subjects

From: Association between P2Y1 and P2Y12 polymorphisms and acute myocardial infarction and ADP-induced platelet aggregation

SNP

Genotype

Healthy subjects

P value

AMI

P value

No

MAR (%)

No

MAR (%)

P2Y1 c.1622A > G

AA

28

44.85 ± 5.64

 

38

83.87 ± 0.87

 
 

AG + GG

22

44.86 ± 4.95

0.995

23

84.43 ± 1.09

0.688

P2Y12 H1/H2

H1/H1

41

44.05 ± 4.99

 

42

84.02 ± 0.83

 
 

H1/H2 + H2/H2

9

48.53 ± 5.35

0.020*

19

84.21 ± 1.19

0.899

P2Y12 c.34C > T

CC

32

44.56 ± 5.15

 

43

83.51 ± 0.86

 
 

CT + TT

18

45.38 ± 5.65

0.605

18

85.44 ± 0.96

0.281

  1. SNP single nucleotide polymorphism
  2. *P < 0.05. P < 0.05 means a significant difference