Fig. 4

Predictive performance and clinical utility of the parameters in the stepwise regression model. A Receiver operating characteristic curves of LA diameter, LAV pre-ac, LAEF passive, LA GLS booster, LV SV, and heart rate for prediction of adverse clinical events at 3 years; B decision curve analysis of LA diameter, LAV pre-ac, LAEF passive, LV SV, LA GLS booster and heart rate at 3 years to predict adverse clinical events in HCM patients. The y-axis represents the net benefit. The x-axis represents the threshold probability, which means that the expected benefit of treatment is equivalent to the expected benefit of non-treatment. The numbers in parentheses are the areas under the receiver operating characteristic curves (AUCs) and 95% confidence intervals (CIs). LA, left atrium; LAV, left atrial volume; pre-ac, pre-contraction; LAEF, left atrial ejection fraction; GLS, global longitudinal strain; LV, left ventricular; SV, stroke volume