Table 2 Pressure and arterial stiffness according to FBN1 genotype in AAA and controls
From: No differences in FBN1 genotype between men with and without abdominal aortic aneurysm
FBN1 2/2 | p value | FBN1 2/3 | p value | FBN1 2/4 | p value | ||||
|---|---|---|---|---|---|---|---|---|---|
AAA (n = 99) | Control (n = 45) | AAA (n = 13) | Control (n = 10) | AAA (n = 47) | Control (n = 15) | ||||
SBP (mmHg) | 133 ± 17.7 | 127 ± 12.7 | 0.058 | 132 ± 25.4 | 138 ± 15.1 | 0.577 | 132 ± 14.4 | 133 ± 16.1 | 0.765 |
DBP (mmHg) | 76 ± 9.1 | 74 ± 7.9 | 0.171 | 74 ± 8.0 | 78 ± 8.7 | 0.238 | 78 ± 7.8 | 77 ± 6.7 | 0.758 |
PPP (mmHg) | 57 ± 15.2 | 54 ± 12.0 | 0.079 | 58 ± 21.5 | 59 ± 12.1 | 0.525 | 54 ± 11.8 | 55 ± 12.0 | 0.863 |
MAP (mmHg) | 97 ± 11.9 | 93 ± 9.6 | 0.054 | 95 ± 14.9 | 99 ± 11.1 | 0.525 | 97 ± 10.2 | 95 ± 9.8 | 0.863 |
ABPI (mmHg) | 1.08 ± 0.17 | 1.17 ± 0.92 | < 0.001 | 1.18 ± 0.13 | 1.19 ± 0.10 | 0.751 | 1.14 ± 0.12 | 1.19 ± 0.15 | 0.512 |
Per AIx HR75 (%) | 82.1 ± 11.6 | 74.0 ± 12.9 | < 0.001 | 78 ± 14.9 | 76 ± 5.0 | 0.713 | 81 ± 11.2 | 71 ± 9.4 | 0.007 |
AIx HR75 (%) | 25.3 ± 6.7 | 20.4 ± 8.3 | < 0.001 | 23 ± 10.0 | 23 ± 5.5 | 0.867 | 25.0 ± 6.8 | 19 ± 5.9 | 0.016 |
CSBP (mmHg) | 125.4 ± 17.3 | 118.2 ± 13.4 | 0.019 | 124 ± 26.1 | 129 ± 16.4 | 0.462 | 124 ± 14.2 | 120 ± 12.4 | 0.445 |
CDBP (mmHg) | 77 ± 9.3 | 75 ± 8.0 | 0.174 | 75 ± 7.9 | 80 ± 8.7 | 0.229 | 79 ± 8.2 | 77 ± 6.7 | 0.429 |
CPP (mmHg) | 48 ± 14.1 | 43 ± 12.8 | 0.054 | 49 ± 22.2 | 49 ± 12.0 | 0.525 | 45 ± 11.8 | 43 ± 10.0 | 0.863 |
PWVcf (m/s) | 12.4 ± 3.0 | 11.0 ± 2.1 | 0.004 | 11.7 ± 3.3 | 11.3 ± 1.9 | 0.943 | 12.4 ± 2.8 | 12.2 ± 3.4 | 0.340 |
PWVcr (m/s) | 9.4 ± 1.16 | 9.0 ± 1.03 | 0.069 | 9.5 ± 1.3 | 9.0 ± 1.0 | 0.483 | 9.5 ± 1.3 | 9.4 ± 0.90 | 0.882 |
HR (bpm) | 59 ± 8.1 | 58 ± 8.9 | 0.492 | 59 ± 9.2 | 59 ± 9.6 | 0.808 | 62 ± 9.6 | 60 ± 8.4 | 0.669 |