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Table 3 Repeated measures ANOVA on major study variables of two groups

From: Music therapy for pain and anxiety in patients after cardiac valve replacement: a randomized controlled clinical trial

Variables

Experimental group (n = 43)

Control group (n = 43)

LS mean (95% CI)

t

P

Time*Group

Pain

     

Interaction P

 1st Post-test

6.02 ± 2.10

7.01 ± 2.22

1.04 (0.76–1.32)#

0.798

0.030##

 < 0.001*

 2nd Post-test

4.40 ± 1.38

5.87 ± 1.50

1.30 (0.87–1.42)#

5.021

 < 0.001##

 3rd Post-test

2.03 ± 1.26

3.85 ± 1.24

1.72 (1.14–2.09)#

7.854

 < 0.001##

  F*

146.36

88.43

   

  P

 < 0.001*

 < 0.001*

   

Anxiety

     

Interaction P

 1st Post-test

52.10 ± 5.50

54.79 ± 6.72

2.98 (1.68–3.65)#

3.132

0.002##

 < 0.001*

 2nd Post-test

42.73 ± 4.92

46.62 ± 6.51

4.80 (3.96–5.37)#

4.138

 < 0.001##

 3rd Post-test

35.53 ± 5.08

41.43 ± 5.49

7.21 (5.92–9.10)#

6.214

 < 0.001##

  F*

117.44

49.38

   

  P

 < 0.001*

 < 0.001*

   

  SBP

     

Interaction P

 1st Post-test

125.31 ± 12.28

132.02 ± 14.67

8.76 (5.88–9.58)#

3.300

0.001##

 < 0.001*

 2nd Post-test

120.63 ± 10.18

128.68 ± 12.33

9.80 (6.67–11.74)#

4.235

 < 0.001##

 3rd Post-test

114.29 ± 7.67

125.02 ± 8.45

10.51 (8.68–13.25)#

6.665

 < 0.001##

  F*

26.10

1.245

   

  P

 < 0.001*

0.233

   

DBP

     

Interaction P

 1st Post-test

81.55 ± 7.99

82.77 ± 7.83

1.51 (0.99–2.15)#

0.720

0.475##

0.242

 2nd Post-test

75.86 ± 6.68

77.30 ± 6.60

2.00 (0.99–2.92)#

1.103

0.310##

 3rd Post-test

71.61 ± 7.51

73.91 ± 6.70

2.22 (1.31–2.54)#

1.519

0.137##

  F*

1.510

1.427

   

  P

0.198

0.203

   

  HR

     

Interaction P

 1st Post-test

83.61 ± 10.71

88.62 ± 10.86

8.99 (5.95–11.08)#

2.670

0.010##

 < 0.001*

 2nd Post-test

80.63 ± 9.22

86.57 ± 8.89

8.80 (6.87–12.34)#

3.301

0.001##

 3rd Post-test

76.92 ± 9.31

82.21 ± 8.92

8.95 (6.84–12.67)#

3.153

0.007##

  F*

55.57

47.65

   

  P

 < 0.001*

 < 0.001*

   

  RR

     

Interaction P

 1st Post-test

19.49 ± 2.99

20.21 ± 3.22

2.30 (1.25–3.04)#

1.375

0.279##

 < 0.001*

 2nd Post-test

17.51 ± 3.18

19.19 ± 2.43

2.60 (1.58–3.37)#

2.853

0.005##

 3rd Post-test

17.03 ± 2.53

18.62 ± 2.15

2.44 (1.55–3.44)#

4.220

 < 0.001##

  F*

66.66

58.85

   

  P

 < 0.001*

 < 0.001*

   
  1. Data are presented as mean ± SD or median (interquartile range), categorical variables are presented as number (%)
  2. F*, Greenhouse–Geisser correction (Failure to pass the Mauchly’s test of sphericity)
  3. LS mean, Least mean difference
  4. REANOVA repeated measured analysis of variance, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, RR respiratory rate
  5. ##Analysis of covariance (take baseline value as covariate)
  6. Time = pretest versus posttest; Time*Group = Interaction