Fig. 2
A Atrial fibrillation patients who were taking warfarin and who had a low SAMe-TT2R2 score (0–2) compared among different percentages of time in therapeutic range. B Atrial fibrillation patients who were taking NOACs compared between those with a SAMe-TT2R2 score 0–2 and those with a SAMe-TT2R2 score 3–8. Abbreviation: TTR, time in therapeutic range; NOACs, non-vitamin K antagonist oral anticoagulants; SAMe-TT2R2 score, S = female sex (1 point); A = age < 60 years (1 point); Me = medical history > 2 of the following: hypertension, diabetes, coronary artery disease/myocardial infarction, peripheral arterial disease, congestive heart failure, previous stroke, pulmonary disease, and hepatic or renal disease (1 point); T = treatment (interacting drugs, e.g., amiodarone for rhythm control) (1 point); T2 = tobacco use within 2 years (2 points); and, R2 = non-Caucasian race (2 points)