Table 1 General patient baseline characteristics (A) and cardiac magnetic resonance imaging (CMR) findings (B), total sample (n = 98) and according to LVEF (n (%), unless otherwise indicated

A. Baseline characteristics

Age (mean ± SD), years

64.0 ± 13.0

66.6 ± 12.4

60.7 ± 12.7

0.023

Male

70/98 (71.4%)

37/52 (71.2%)

33/46 (71.7%)

0.949

Hypertension

66/98 (67.4%)

35/52 (67.3%)

31/46 (67.4%)

0.993

Diabetes

29/98 (29.6%)

17/52 (32.7%)

12/46 (26.1%)

0.475

Hypercholesterolaemia

36/98 (36.7%)

19/52 (36.5%)

17/46 (37%)

0.966

Smoking

45/98 (45.9%)

23/52 (44.2%)

22/46 (47.8%)

0.722

Etiological diagnosis

N.A

 Idiopathic

74/98 (75.6%)

42/52 (80.8%)

32/46 (69.6%)

 Enolic

10/98 (10.2%)

5/52 (9.6%)

5/46 (10.9%)

 Not compacted

5/98 (5.1%)

2/52 (3.8%)

3/46 (6.5%)

 Tachymyocardiopathy

3/98 (3.1%)

1/52 (1.9%)

2/46 (4.3%)

 Peripartum cardiomyopathy

2/98 (2%)

0/52 (0%)

2/46 (4.3%)

 Myocarditis

2/98 (2%)

1/52 (1.9%)

1/46 (2.2%)

 Genetic

1/98 (1%)

0/52 (0%)

1/46 (2.2%)

 Cardiotoxicity

1/98 (1%)

1/52 (1.9%)

0/46 (0%)

Treatment

 Beta blockers

91/98 (92.9%)

49/52 (94.2%)

42/46 (91.3%)

0.703

 ACEIs/ARBs

77/98 (78.6%)

38/52 (73.1%)

39/46 (84.1%)

0.501

 Antialdosteronics

60/98 (61.2%)

37/52 (71.2%)

23/46 (50%)

0.032

 Sacubitril-valsartan

9/98 (9.2%)

5/52 (9.6%)

4/46 (8.7%)

1

 Ivabradine

12/98 (12.2%)

5/52 (9.6%)

7/46 (15.2%)

0.399

 Furosemide

53/98 (54.2%)

33/52 (63.5%)

20/46 (43.5%)

0.048

B. CMR findings

EDV/BSA LV (mean ± SD), ml/m2

133.6 ± 33.4

149.1 ± 32.4

116.1 ± 24.9

< 0.001

LVEF (%)

29.5 ± 9.6%

22.0 ± 4.3%

38.0 ± 6.2%

< 0.001

EDV/BSA RV (mean ± SD), ml/m2

71.6 ± 20.5

72.0 ± 19.6

71.0 ± 21.7

0.82

RVEF (%)

52.2 ± 14.6

44.9 ± 14.7

60.4 ± 9.2

< 0.001

Non-ischemic LGE

38/98 (38.8%)

21/52 (40.4%)

17/46 (37.0%)

0.728

RVEF < 45%

26/98 (26.5%)

24/52 (46.2%)

2/46 (4.3%)

< 0.001

Feature tracking-RV

 LFT-RVFW (mean ± SD)

− 23.8 ± 9.9%

− 19.0 ± 6.8%

29.2 ± 10.1%

0.006

 FAC (mean ± SD)

39.7 ± 16.6%

32.8 ± 15.8%

47.5 ± 13.9%

< 0.001

LFT-RVFW < − 18.5%

36/98 (36.7%)

30/52 (57.7%)

6/46 (13.0%)

< 0.001

FAC < 32%

33/98 (33.7%)

28/52 (53.8%)

5/46 (10.9%)

< 0.001

C. Mortality

Cardiovascular deaths

3/98 (3.1%)

1/52 (2.0%)

2/46 (4.3%)

0.602

Other causes

5/98 (5.1%)

5/52 (9.8%)

0/46 (0.0%)

0.058