Thyroid hormone, cortisol, interleukin-2, and procalcitonin regulate postoperative delirium in acute type A aortic dissection patients

Table 2 Univariate and multivariate logistic regression analysis of the related significant hormones and inflammatory predictors of POD in AAD patients

Variables	Univariate analysis		Multivariate analysis
Variables	OR(95%CI)	P-value	OR(95%CI)	P-value
Preoperative FT3 (pmol/L)	0.672 (0.482, 0.802)	0.008	0.880 (0.665, 0.941)	0.032
Preoperative FT4 (pmol/L)	0.856 (0.539, 0.961)	0.024	0.877 (0.601, 1.312)	0.240
Preoperative cortisol (nmol/l)	1.018 (1.013,1.024)	< 0.001	1.019 (1.013,1.025)	< 0.001
Preoperative IL-2 (pg/ml)	2.351 (1.510,3.660)	< 0.001	2.497 (1.478,4.218)	0.001
Preoperative PCT (ng/mL)	6.544 (1.551,27.605)	0.011	7.768 (1.471,41.022)	0.016

Univariate analysis adjusted for: None
Multivariate analysis adjusted for: age; sex; body mass index; drinking history; serum total bilirubin; platelet; hemoglobin; creatinine; intraoperative transfusion of packed red blood cell; deep hypothermic circulatory arrest time; cardiopulmonary bypass time; aortic cross clamp time
Bold mean statistical significances were determined due to a two-tailed P value < 0.05
POD postoperative delirium, FT3 free triiodothyronine, FT4 free thyroxine, TSH thyroid stimulating hormone, IL-2 interleukin-2, PCT procalcitoninis, AAD acute aortic dissection, OR odds ratio, CI confidence interval

ISSN: 1471-2261