A simple APACHE IV risk dynamic nomogram that incorporates early admitted lactate for the initial assessment of 28-day mortality in critically ill patients with acute myocardial infarction

Table 3 NRI and IDI analyses for models containing Admission early lactate (A) and Admission early lactate, AF, Gender (B) in addition to APACHE IV score

	NRI	P-value	IDI	P-value
(A) Lactate with APACHE IV score
Among event subjects	4.7%	0.2818
Among non-event subjects	3.4%	0.0743
Overall (95% bootstrap CI)	8% (− 1.2–17.2%)	0.0895	8% (− 1.3–17.3%)	0.0911
(B) Three variables with APACHE IV score
Among event subjects	3.5%	0.4655
Among non-event subjects	12.9%	< 0.0001
Overall (95% bootstrap CI)	16.4% (6.1–26.8%)	0.0019	16.4% (6.0–26.8%)	0.0020

NRI, Net reclassification improvement; IDI, Integrated discrimination improvement; AF, atrial fibrillation

ISSN: 1471-2261