Table 3 Determinants of discrepantly higher or lower pulmonary arterial systolic pressure compared to E/e′
Variables | Higher PASP compared to E/e′ (Group 1, n = 50) | On the regression line between PASP and E/e′ (Group 2, n = 28) | Lower PASP compared to E/e′ (Group 3, n = 55) | Overall p value | |
|---|---|---|---|---|---|
HCM | LA-GLS (%) | 17.5 (10.5, 22.4) | 18.7 (14.9, 23.0) | 20.8 (15.1, 27.1) | 0.063 |
LAVImax (mL/m2) | 80.9 (65.3, 98.2) | 58.3 (45.3, 68.9)* | 56.2 (46.7, 74.6)* | < 0.001 | |
LAVImin (mL/m2) | 47.7 (33.2, 75.3) | 30.4 (25.6, 38.8)* | 30.0 (21.4, 39.5)* | < 0.001 | |
LA preA volume index (mL/m2) | 59.1 (39.6, 74.2) | 46.1 (33.4, 55.8) | 43.2 (33.4, 55.9)* | 0.011 | |
LA total emptying fraction (%) | 37.2 ± 15.8 | 45.9 ± 8.8 | 45.9 ± 13.2* | 0.002 | |
LA reservoir fraction (%) | 61.3 (31.7, 96.6) | 87.2 (69.4, 100.0) | 88.5 (67.4, 119.5)* | 0.014 | |
LA conduit fraction (%) | 26.2 (18.2, 40.5) | 26.0 (18.8, 33.0) | 27.2 (17.2, 36.9) | 0.855 | |
LA active emptying fraction (%) | 27.7 ± 12.2 | 31.5 ± 8.9 | 31.8 ± 13.1 | 0.242 | |
E/e′/LA-GLS (%) | 0.9 (0.5, 1.5) | 0.6 (0.5, 0.9) | 0.7 (0.6, 1.1) | 0.219 | |
ECVavg (%) | 33.1 ± 5.1 | 31.3 ± 4.8 | 31.9 ± 4.1 | 0.261 | |
LVMI (by TTE) (g/m2) | 128.6 (108.8, 152.0) | 105.01 (94.6, 120.0)* | 121.6 (104.3, 135.4) | 0.006 | |
LVEF (by TTE) (%) | 69 (65, 72) | 70 (65, 73) | 70 (66, 73) | 0.637 |
Variables | (Group 1, n = 45) | (Group 2, n = 16) | (Group 3, n = 53) | ||
|---|---|---|---|---|---|
DCM | LA-GLS (%) | 7.5 (3.5, 11.8) | 6.7 (3.4, 8.0)† | 11.5 (6.9, 23.1)* | 0.001 |
LAVImax (mL/m2) | 76.1 (60.8, 108.3) | 70.0 (63.7, 81.4)† | 52.3 (41.6, 74.5)* | < 0.001 | |
LAVImin (mL/m2) | 60.3 (44.3, 86.6) | 53.7 (46.6, 68.9)† | 34.8 (20.8, 51.5)* | < 0.001 | |
LA preA volume index (mL/m2) | 63.6 (50.5, 84.9) | 61.1 (51.7, 70.0)† | 41.3 (29.9, 57.8)* | < 0.001 | |
LA total emptying fraction (%) | 24.8 (17.7, 30.2) | 20.0 (17.4, 26.1)† | 36.1 (23.9, 50.0)* | < 0.001 | |
LA reservoir fraction (%) | 33.0 (21.5, 43.3) | 24.9 (21.1, 35.4)† | 56.5 (31.3, 100.0)* | < 0.001 | |
LA conduit fraction (%) | 15.5 (4.6, 21.5) | 11.0 (9.4, 15.0) | 19.7 (12.0, 33.7)* | 0.006 | |
LA active emptying fraction (%) | 12.1 (8.1, 20.4) | 9.6 (8.3, 18.9)† | 26.4 (16.0, 35.7)* | 0.002 | |
E/e′/LA-GLS (%) | 2.7 (1.3, 5.4) | 4.1 (2.8, 6.0)† | 1.3 (0.5, 2.4)* | 0.011 | |
ECVavg (%) | 35.4 ± 5.4 | 31.6 ± 2.5 | 32.5 ± 3.8* | 0.005 | |
LVMI (by TTE) (g/m2) | 134.3 ± 30.3 | 127.4 ± 31.5 | 125.6 ± 42.3 | 0.491 | |
LVEF (by TTE) (%) | 20 (15, 26) | 18 (15, 23)† | 29 (20, 40)* | < 0.001 |