Table 2 Differential contribution of the left atrial volume, function, and left ventricular fibrosis on the pulmonary arterial systolic pressure in hypertrophic cardiomyopathy and dilated cardiomyopathy
HCM | DCM | |||||||
|---|---|---|---|---|---|---|---|---|
Univariable analysis | Multivariable analysis | Univariable analysis | Multivariable analysis | |||||
B (95% CI) | p value | B (95% CI) | p value | B (95% CI) | p value | B (95% CI) | p value | |
Echocardiography | ||||||||
LV-EF (%) | − 0.2 (− 0.4, − 0.04) | 0.02 | − 0.1 (− 0.3, 0.03) | 0.09 | − 0.3 (− 0.6, − 0.1) | 0.005 | − 0.2 (− 0.5, 0.02) | 0.08 |
e′ (cm/s) | − 30.4 (− 105.6, 44.8) | 0.43 | − 114.3 (− 240.2, 11.6) | 0.08 | ||||
s′ (cm/s) | − 83.7 (− 155.7, − 11.7) | 0.02 | − 157.2 (− 348.9, 34.4) | 0.11 | ||||
E/e′ | 0.4 (0.1, 0.6) | 0.001 | 0.1 (− 0.1,0.3) | 0.30 | 0.6 (0.3, 0.8) | < 0.001 | 0.07 (− 0.2, 0.4) | 0.66 |
CMR | ||||||||
LA-GLS (%) | − 0.2 (− 0.4, − 0.1) | < 0.001 | − 0.02 (− 0.3, 0.3) | 0.87 | − 0.7 (− 1.0, − 0.4) | < 0.001 | − 0.2 (− 0.6, 0.3) | 0.49 |
LAVImax (mL/m2) | 0.1 (0.1, 0.2) | < 0.001 | 0.12 (0.07, 0.2) | < 0.001 | 0.2 (0.1, 0.3) | < 0.001 | 0.1 (0.03, 0.3) | 0.02 |
LAVImin (mL/m2) | 0.1 (0.1, 0.2) | < 0.001 | 0.2 (0.1, 0.3) | < 0.001 | ||||
LA total emptying fraction (%) | − 0.2 (− 0.3, − 0.1) | < 0.001 | − 0.4 (− 0.6, − 0.2) | < 0.001 | ||||
LA reservoir fraction (%) | − 0.05 (− 0.08, − 0.03) | < 0.001 | − 0.01 (− 0.04, 0.02) | 0.43 | − 0.1 (− 0.2, − 0.06) | < 0.001 | ||
LV-ECVavg (%) | 0.3 (0.04, 0.6) | 0.03 | − 0.04 (− 0.3, 0.3) | 0.80 | 1.3 (0.7, 1,9) | < 0.001 | 1.1 (0.5, 1.6) | < 0.001 |
E/e′/LA-GLS (%) | 1.8 (1.0, 2.7) | < 0.001 | 0.09 (0.06, 1.7) | 0.04 | 1.0 (0.5, 1.6) | < 0.001 | 0.6 (0.06, 1.2) | 0.03 |