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Fig. 5 | BMC Cardiovascular Disorders

Fig. 5

From: Resistance exercise promotes the resolution and recanalization of deep venous thrombosis in a mouse model via SIRT1 upregulation

Fig. 5

Collagen content and IL-10, IL-6, and TNF-a expression levels on days 14 and 28. (a) Masson’s trichrome staining of the IVC of the groups at the indicated time points; representative pictures are shown. Magnification: × 100. Scale bar: 200 µm. (b) Summary of the quantitative analysis of the collagen contents of venous thrombi for MTC staining per group on days 14 and 28 (n = 3–5 mice). IL-6 (c), TNF-a (d), and IL-10 (e) protein concentrations of the mice in each group were measured through ELISA on days 14 and 28 (n = 6 mice). mRNA expression levels of IL-6 (f) and IL-10 (g) within the thrombus were determined through RT-qPCR (n = 5 mice). Data are expressed as the means ± SD and analyzed through one-way ANOVA (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001). C: Control group; D: DVT group; ED: exercise and DVT group; IED: SIRT1 inhibitor, exercise DVT group

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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