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Table 3 Predictive value of LDH for in-hospital mortality in different models

From: Impact of lactate dehydrogenase on prognosis of patients undergoing cardiac surgery

  Unadjusted Model I Model II
OR (95% Cl) P OR (95% Cl) P OR (95% Cl) P
MIMIC III*       
 LDH as continuous variablea 1.00 (1.00–1.00) < 0.001 1.00 (1.00–1.00) < 0.001 1.00 (1.00–1.00) < 0.001
 LDH as nominal variableb 6.20 (3.85–9.98) < 0.001 4.79 (2.93–7.83) < 0.001 4.90 (2.96–8.09) < 0.001
MIMIC IV**       
 LDH as continuous variablea 1.00 (1.00–1.00) < 0.001 1.00 (1.00–1.00) 0.002 1.00 (1.00–1.00) 0.004
 LDH as nominal variableb 5.01 (2.52–9.97) < 0.001 3.29 (1.54–7.06) 0.002 3.80 (1.82–7.95) < 0.001
  1. aThe OR was examined by per 1-point increase of LDH
  2. bThe OR was examined regarding the low LDH as reference
  3. *MIMIC III
  4.   Model 1: adjusted for ethnicity, SBP, heart rate, hypertension, CHD, heart failure
  5.   Model 2: adjusted for BUN, SCr, sodium, potassium, glucose, SAPS II, SOFA score
  6. **MIMIC IV
  7.   Model 1: adjusted for hypertension, heart_failure, CKD, WBC
  8.   Model 2: adjusted for BUN, SCr, sodium, potassium, SAPS II
  9. OR odds ratio, 95% CI 95% confidence interval, MIMIC Medical Information Mart for Intensive Care, LDH lactate dehydrogenase