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Table 3 Predictive value of LDH for in-hospital mortality in different models

From: Impact of lactate dehydrogenase on prognosis of patients undergoing cardiac surgery

 

Unadjusted

Model I

Model II

OR (95% Cl)

P

OR (95% Cl)

P

OR (95% Cl)

P

MIMIC III*

      

 LDH as continuous variablea

1.00 (1.00–1.00)

< 0.001

1.00 (1.00–1.00)

< 0.001

1.00 (1.00–1.00)

< 0.001

 LDH as nominal variableb

6.20 (3.85–9.98)

< 0.001

4.79 (2.93–7.83)

< 0.001

4.90 (2.96–8.09)

< 0.001

MIMIC IV**

      

 LDH as continuous variablea

1.00 (1.00–1.00)

< 0.001

1.00 (1.00–1.00)

0.002

1.00 (1.00–1.00)

0.004

 LDH as nominal variableb

5.01 (2.52–9.97)

< 0.001

3.29 (1.54–7.06)

0.002

3.80 (1.82–7.95)

< 0.001

  1. aThe OR was examined by per 1-point increase of LDH
  2. bThe OR was examined regarding the low LDH as reference
  3. *MIMIC III
  4.   Model 1: adjusted for ethnicity, SBP, heart rate, hypertension, CHD, heart failure
  5.   Model 2: adjusted for BUN, SCr, sodium, potassium, glucose, SAPS II, SOFA score
  6. **MIMIC IV
  7.   Model 1: adjusted for hypertension, heart_failure, CKD, WBC
  8.   Model 2: adjusted for BUN, SCr, sodium, potassium, SAPS II
  9. OR odds ratio, 95% CI 95% confidence interval, MIMIC Medical Information Mart for Intensive Care, LDH lactate dehydrogenase
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BMC Cardiovascular Disorders

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