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Table 3 Bivariable and multivariable results from the logistic regression analysis regarding sarcopenia status (n = 132)

From: Statins are associated with reduced likelihood of sarcopenia in a sample of heart failure outpatients: a cross-sectional study

 

Unadjusted

Adjusted

OR (95% CI)

p-value

OR (95% CI)

p-value

Statin

 No

1

 

1

 

 Yes

0.39 (0.16, 0.96)

0.040

0.03 (0.01, 0.30)

0.003

Age, years

1.04 (0.99, 1.08)

0.077

1.09 (1.01, 1.17)

0.022

Sex

 Women

1

 

1

 

 Men

0.04 (0.01, 0.14)

 < 0.001

0.01 (0.00, 0.07)

 < 0.001

LVEF categories

 HFpEF

1

 

1

 

 HFmrEF

2.14 (0.66, 6.93)

0.203

5.07 (0.61, 42.14)

0.133

 HFrEF

2.40 (0.86, 6.73)

0.096

3.78 (0.60, 25.07)

0.169

NYHA functional classes

 NYHA Class I

1

 

1

 

 NYHA Class II

2.74 (0.92, 8.12)

0.068

4.82 (0.41, 56.56)

0.211

 NYHA Class III

2.10 (0.50, 8.82)

0.311

14.65 (0.73, 293.72)

0.079

HF aetiology

 Ischaemic

1

 

1

 

 Others

1.63 (0.56, 4.73)

0.368

1.30 (0.20, 8.40)

0.781

Polypharmacy

  < 5 medicines/day

1

 

1

 

  ≥ 5 medicines/day

2.99 (0.85, 10.72)

0.093

26.87 (2.01, 359.26)

0.013

Physical activity

 Inactive

1

 

1

 

 Minimally active + active

0.25 (0.09, 0.70)

0.009

0.09 (0.01, 0.65)

0.017

Body mass index, Kg.m−2

0.92 (0.82, 1.02)

0.124

0.79 (0.65, 0.96)

0.017

Total fat intake, g/Kg/day

0.72 (0.26, 2.04)

0.538

0.34 (0.02, 5.20)

0.437

  1. Values are expressed in Odds Ratio (OR) and 95% Confidence Intervals (95% CI). HF = Heart Failure; LVEF = Left Ventricular Ejection Fraction; HFrEF = Heart Failure with reduced Ejection Fraction; HFmrEF = Heart Failure with mildly reduced Ejection Fraction; HFpEF = Heart Failure with preserved Ejection Fraction. Omnibus test: p < 0.001; Nagelkerke R-square = 0.706; Hosmer and Lemeshow test: p = 0.801. Model sensitivity: 76.0%; Model specificity: 95.3%. Model accuracy: 91.7%